Vasitis nodosa

Testis and epididymis
Non-neoplastic lesions
Vasitis nodosa

Author: Rafael Jimenez, M.D. (see Authors page)

Revised: 25 May 2017, last major update March 2012

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PubMed Search: vasitis nodosa

Table of Contents

Definition / general | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis

Cite this page: Vasitis nodosa. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/testisvasitisnodosa.html. Accessed July 15th, 2017.

Definition / general

Granulomatous condition of vas deferens that resembles spermatic granuloma of epididymis
Usually post vasectomy or herniorrhaphy
Occasionally associated with recanalization

Microscopic (histologic) description

Proliferating ductules and dilated tubules containing spermatozoa in wall of vas deferens
Also associated with small bundles of hyperplastic smooth muscle
Vas deferens may show irregular thickening
Ductules may connect with vas deferens (like diverticula or salpingitis isthmica nodosa but with inflammation and less smooth muscle hypertrophy)
May see perineural or vascular invasion by proliferating ductules

Microscopic (histologic) images

Images hosted on other servers:

Sperm granuloma

Extravasated spermatozoa

Atypical nuclei

Nodular enlargement

Sperm granulomas

Proliferating ductules

Differential diagnosis

Adenocarcinoma of epididymis and adenocarcinoma of rete testis: no history of prior surgery, no intraluminal spermatozoa