Thyroid gland
Thyroiditis
Autoimmune thyroiditis


Topic Completed: 1 March 2009

Minor changes: 16 September 2020

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PubMed Search: autoimmune thyroiditis thyroid

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Autoimmune thyroiditis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidautoimmune.html. Accessed October 20th, 2020.
Definition / general
  • Nonneoplastic thyroid disorders with antithyroid antibodies and associated with specific HLA haplotypes
  • #1 cause of hypothyroidism in iodine sufficient areas
  • Includes Graves' disease, Hashimoto's thyroiditis and most forms of thyroiditis in this section except infectious
  • Rosai differentiates based on follicular epithelium: lymphocytic thyroiditis if relatively normal follicles, Hashimoto's thyroiditis if oncocytic change, Graves' disease if diffusely hyperplastic follicles
Epidemiology
Clinical features
  • May be due to disturbance in suppressor T cells
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