Thyroid gland
Autoimmune thyroiditis

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 12 January 2017, last major update March 2009

Copyright: (c) 2003-2017,, Inc.

PubMed Search: autoimmune thyroiditis thyroid
Cite this page: Autoimmune thyroiditis. website. Accessed March 24th, 2018.
Definition / general
  • Nonneoplastic thyroid disorders with antithyroid antibodies and associated with specific HLA haplotypes
  • #1 cause of hypothyroidism in iodine sufficient areas
  • Includes Graves' disease, Hashimoto's thyroiditis and most forms of thyroiditis in this section except infectious
  • Rosai differentiates based on follicular epithelium: lymphocytic thyroiditis if relatively normal follicles, Hashimoto's thyroiditis if oncocytic change, Graves' disease if diffusely hyperplastic follicles
Clinical features
  • May be due to disturbance in suppressor T cells