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Follicular cell derived - papillary thyroid carcinoma

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See also PathologyOutlines - papillary carcinoma

Papillary architecture
Sheets of cells with sparse colloid
Classic nuclear features
Focal nuclear crowding and nuclear grooves
Intranuclear inclusions
Ground glass nuclei
Psammoma bodies
Cell block
Cellular swirls
Metaplastic squamous cells
Classical type, contributed by Dr. Mark R. Wick


Follicular cell derived - poorly differentiated carcinoma

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See also PathologyOutlines - insular carcinoma

Nesting pattern of cells
Cellular smear has overlapping cells with round, regular nuclei
Large clusters and single cells, inset shows vacuolated cytoplasm
Cellular nests of loosely cohesive cells
Overlapping cells with mild atypia
Small microfollicle of tumor cells
Cells have finely vacuolated cytoplasm and round / oval nuclei


Follicular cell derived - anaplastic carcinoma

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See also PathologyOutlines - anaplastic carcinoma

Bizarre tumor giant cells
Atypical cells
Giant cell type has large, bizarre cells
Spindle cell type has dyscohesive spindled cells


Follicular cell derived - other

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Squamous cell carcinoma:

Atypical pleomorphic cells

Metastases from larynx

Metastases from esophagus



C-Cell derived - medullary thyroid carcinoma

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Dyscohesive plasmacytoid cells

Spindled cells with scanty ill-defined cytoplasm

Orange granular amyloid material

Spindle cells

Atypical spindle cells



Lymphoma

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Diffuse large B cell lymphoma:

Large and irregular lymphoid cells

High grade lymphoma shows atypical cells

Large cell type, contributed by Dr. Mark R. Wick

Diffuse large B cell lymphoma misdiagnosed as anaplastic carcinoma

CD45/LCA+, CD20+, keratin negative


Other:
Intermediate grade lymphoma
MALT lymphoma
Metastatic carcinoma

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Esophageal squamous cell carcinoma
Lung squamous cell carcinoma
Melanoma
Melanoma - HMB45
Parotid gland adenoid cystic carcinoma
End of Thyroid > Competency Assessment > Malignant



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