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General
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Case reports
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Treatment
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Gross description
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Gross images
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Lobular with white, shiny,
cartilaginous elements (AFIP)

Micro description
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Micro images
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Tumor cells arranged in nests

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Spindle-shaped cells, abundant, granular, eosinophilic cytoplasm

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Vesicular chromatin distribution

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Various images

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PAS+

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Courtesy of Dr. Mark R. Wick



AFIP Images:

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Twisting trabeculae

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Prominent nesting

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Nuclear grooves (arrows) and pseudoinclusions (arrowhead)

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Psammoma body

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Intraluminal and cytoplasmic thyroglobulin



Other tumors that appear similar:

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Trabecular variant of papillary carcinoma

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Large cytoplasmic bodies in other tumors

Cytology description
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Cytology images
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Elongated tumor with acellular stroma

Electron Microscope
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Positive stains
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Negative stains
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Molecular
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Differential diagnosis
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End of Thyroid > Benign neoplasms > Hyalinizing trabecular neoplasm



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