Thyroid gland
Thyroiditis
Infectious thyroiditis



Topic Completed: 1 March 2009

Revised: 11 March 2019

Copyright: 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: infectious thyroiditis

Related Topic: Tuberculous thyroiditis

Shahid Islam, M.D., Ph.D.
Page views in 2018: 764
Page views in 2019 to date: 480
Cite this page: Shahid I. Infectious thyroiditis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidinfectious.html. Accessed July 18th, 2019.
Definition / general
  • Also called acute thyroiditis
  • Via blood or direct seeding from upper respiratory infections, causes sudden onset of pain and glandular enlargement
  • Risk factors: malnourished infant, debilitated elderly, immunosuppression, trauma
  • Often Streptococcus haemolyticus, Streptococcus pneumoniae, Staphylococcus aureus; gram negative bacteria associated with trauma; also Pneumocystis jiroveci in HIV+ patients with low CD4 counts (Mycoses 2007;50:443)
Clinical features
Diagnosis
  • Usually based on serologic tests
Case reports
Treatment
  • Drainage, antibiotics, fistulectomy
Gross description
  • Normal or slightly enlarged thyroid gland
  • May have suppurative areas
Gross images

Images hosted on other servers:

Aspergillus septic foci

Microscopic (histologic) description
  • Neutrophils, possibly microabscesses and tissue necrosis
  • Fungi are associated with necrosis, acute inflammation and granulomas
Cytology images

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Aspergillus

Nocardia

Stains
  • Gram stain or GMS / PAS may help identify bacteria or fungi; use ISH or IHC for viruses
Differential diagnosis
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