Thyroid gland
Other carcinoma
Insular carcinoma - Poorly differentiated carcinoma with rhabdoid features


Topic Completed: 2 March 2009

Revised: 2 May 2019

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PubMed Search: poorly differentiated carcinoma rhabdoid thyroid

Related Topic: Insular carcinoma

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Insular carcinoma - Poorly differentiated carcinoma with rhabdoid features. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidinsularrhabdoidfeatures.html. Accessed December 10th, 2019.
Definition / general
Case reports
  • 22 year old man with unusual features including presentation in a young male and the absence of either follicular / papillary differentiation (Endocr Pathol 2006;17:399)
  • 42 year old woman with neck mass and 58 year old man with thyroid lobe mass (Mod Pathol 2001;14:98)
Microscopic (histologic) description
  • Prominent cytoplasm with eccentric eosinophilic inclusions, large vesicular nuclei with prominent nucleoli, necrosis and numerous mitotic figures
Positive stains
Negative stains
Differential diagnosis
  • Cytoplasmic thyroglobulin inclusions: round, PAS positive
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