Table of ContentsDefinition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis
Cite this page: Lithium thyroiditis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidlithiumthyroiditis.html. Accessed September 25th, 2018.
Definition / general
- Lithium directly damages thyroid follicular cells, which releases thyroglobulin, which may be hydrolyzed to thyroxine, causing hyperthyroidism
- 53 year old man with sudden cardiac arrest (Case of the Week #139)
Microscopic (histologic) description
- Small follicles with atrophy and minimal colloid; follicles contain desquamated follicular cells, macrophages and multinucleated giant cells; some giant cells contain birefringent calcium oxalate crystals (J Clin Pathol 1995;48:582)