Thyroid gland
Variants of papillary carcinoma
Microcarcinoma variant



Topic Completed: 1 March 2009

Revised: 26 April 2019

Copyright: 2003-2018, PathologyOutlines.com, Inc.

PubMed search: papillary microcarcinoma thyroid


Shahid Islam, M.D., Ph.D.
Page views in 2018: 4,841
Page views in 2019 to date: 2,820
Cite this page: Islam S. Microcarcinoma variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidmicrocarcinomavariant.html. Accessed July 19th, 2019.
Definition / general
Terminology
Prognostic factors
Case reports
Treatment
Gross description
  • Nonencapsulated, sclerotic, white tan nodule, often subcapsular
Gross images

Images hosted on PathOut server:

Unusually well
circumscribed
tumor is focally
cystic and < 2 mm

Typical gross appearance
of irregular, solid
white tumor a few mm
in diameter

Microscopic (histologic) description
  • Variable encapsulation, stellate appearance on low power; resembles classic papillary carcinoma at high power
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Andrey Bychkov, M.D., Ph.D.

Diffuse positive staining for CK19, Galectin-3 and HBME-1

Incidental finding in multinodular goiter

Psammoma bodies in benign appearing thyroid

Encapsulated papillary microcarcinoma



Images from AFIP:

Stellate tumor has marked fibrosis

Resembles multifocal fibrosing thyroiditis

Irregular with marked fibrosis and mononuclear inflammation

Scant fibrosis, nuclear features in inset

Predominant papillary pattern outside capsule



Images hosted on other servers:

Focal sclerosis

H&E

Cytology images

Images hosted on PathOut server:

Pap stained slides

Molecular / cytogenetics description
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