Thyroid gland
Variants of papillary carcinoma
Microcarcinoma variant

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 10 February 2017, last major update March 2009

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: papillary microcarcinoma thyroid

Cite this page: Microcarcinoma variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidmicrocarcinomavariant.html. Accessed June 24th, 2017.
Definition / general
Terminology
Prognostic factors
Case reports
Treatment
Gross description
  • Nonencapsulated, sclerotic, white tan nodule, often subcapsular
Gross images

Images hosted on PathOut server:

Unusually well
circumscribed
tumor is focally
cystic and < 2 mm

Typical gross appearance
of irregular, solid
white tumor a few mm
in diameter

Microscopic (histologic) description
  • Variable encapsulation, stellate appearance on low power; resembles classic papillary carcinoma at high power
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Andrey Bychkov, M.D., Ph.D.:

Diffuse positive staining for CK19, Galectin-3 and HBME-1

Incidental finding in multinodular goiter

Psammoma bodies in benign appearing thyroid

Encapsulated papillary microcarcinoma



Images from AFIP:

Stellate tumor has marked fibrosis

Resembles multifocal fibrosing thyroiditis

Irregular with marked fibrosis and mononuclear inflammation

Scant fibrosis, nuclear features in inset

Predominant papillary pattern outside capsule



Images hosted on other servers:

Focal sclerosis

H&E

Cytology images

Images hosted on PathOut server:

Pap stained slides

Molecular / cytogenetics description