Thyroid gland
Variants of papillary carcinoma
Microcarcinoma variant

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 1 December 2016, last major update March 2009

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: papillary microcarcinoma [title] thyroid

Cite this page: Microcarcinoma variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidmicrocarcinomavariant.html. Accessed December 6th, 2016.
Definition / General
Terminology
Prognostic Factors
Poor prognostic factors:
Case Reports
Treatment
Gross Description
  • Nonencapsulated, sclerotic, white tan nodule, often subcapsular
Gross Images
Images hosted on PathOut server:

Typical gross appear-
ance of irregular, solid
white tumor a few mm
in diameter

Unusually well
circumscribed
tumor is focally
cystic and < 2 mm
Micro Description
  • Variable encapsulation, stellate appearance on low power; resembles classic papillary carcinoma at high power
Micro Images
Images hosted on PathOut server:

Courtesy of Andrey Bychkov, M.D., Ph.D.

Diffuse positive staining for CK19, Galectin-3 and HBME-1



Images from AFIP:

Stellate tumor has marked fibrosis

Resembles multifocal fibrosing thyroiditis

Irregular with marked fibrosis and mononuclear inflammation

Scant fibrosis, nuclear features in inset

Predominant papillary pattern outside capsule



Images hosted on other servers:

Focal sclerosis

H&E

Cytology Images
Images hosted on PathOut server:

Pap stained slides

Molecular / Cytogenetics Description