Thyroid gland
Palpation thyroiditis

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 24 February 2017, last major update March 2009

Copyright: (c) 2003-2017,, Inc.

PubMed search: palpation thyroiditis

Cite this page: Palpation thyroiditis. website. Accessed July 23rd, 2018.
Definition / general
  • Common (85%+ of surgically resected thyroids) but clinically insignificant
  • Also called multifocal granulomatous thyroiditis
Clinical features
Case reports
  • Self limited, no treatment necessary
Gross description
  • Normal, or small foci of hemorrhage
Microscopic (histologic) description
  • Multiple small granulomas centered in disrupted follicles, composed of lymphocytes (usually T cells), macrophages (some foamy), occasional multinucleated giant cells associated with colloid breakdown, usually no necrosis, no neutrophils
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Andrey Bychkov, M.D., Ph.D.:

located nodule
made up of several
disrupted follicles

Burst follicles
with intrafollicular

Granulomatous folliculitis

Multinucleated giant cells replacing colloid within follicle

Images from AFIP:

Histiocytes within follicle #1

#2 - histiocytes are strongly lysozyme+

Images hosted on other servers:


Differential diagnosis