Thyroid gland
Thyroiditis
Palpation thyroiditis




Topic Completed: 1 March 2009

Revised: 15 March 2019

Copyright: 2003-2017, PathologyOutlines.com, Inc.

PubMed search: palpation thyroiditis
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Cite this page: Islam S. Palpation thyroiditis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidpalpation.html. Accessed April 19th, 2019.
Definition / general
  • Common (85%+ of surgically resected thyroids) but clinically insignificant
Terminology
  • Also called multifocal granulomatous thyroiditis
Clinical features
Case reports
Treatment
  • Self limited, no treatment necessary
Gross description
  • Normal, or small foci of hemorrhage
Microscopic (histologic) description
  • Multiple small granulomas centered in disrupted follicles, composed of lymphocytes (usually T cells), macrophages (some foamy), occasional multinucleated giant cells associated with colloid breakdown, usually no necrosis, no neutrophils
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Andrey Bychkov, M.D., Ph.D.:

Superficially
located nodule
made up of several
disrupted follicles

Burst follicles
with intrafollicular
granulomatous
reaction

Granulomatous folliculitis

Multinucleated giant cells replacing colloid within follicle



Images from AFIP:

Histiocytes within follicle #1

#2 - histiocytes are strongly lysozyme+



Images hosted on other servers:

Granuloma

Differential diagnosis
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