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Thyroid gland
Papillary carcinoma

Reviewer: Shahidul Islam, M.D., Ph.D. (see Reviewers page)
Revised: 12 June 2013, last major update March 2009
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

Cytology description
Cytology images
Papillary architecture
Sheets of cells with sparse colloid
Classic nuclear features
Focal nuclear crowding and nuclear grooves
Intranuclear inclusions
Nuclear size variation, microfollicular pattern and intranuclear pseudoinclusion
Ground glass nuclei
Psammoma bodies
Cell block
Cellular swirls
Metaplastic squamous cells
Cystic tumor
Classical type, contributed by Dr. Mark R. Wick
Suspicious for papillary carcinoma:
Suspicious-carcinoma at resection
Rare intranuclear inclusions and abundant colloid - benign at resection
Indeterminate for papillary carcinoma:
Cases difficult to diagnose
Metastatic mucinous papillary carcinoma:
Polygonal cells with intracytoplasmic vacuoles
Signet ring cell
Targetoid cells created by intracellular globules
Globular inclusions
Coarsely vacuolated carcinoma
Vacuoles are mucicarmine+
Positive stains
Differential diagnosis
End of Thyroid gland > Papillary carcinoma > Cytology

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