Thyroid gland
Benign neoplasms
Postoperative spindle cell nodule

Author: Sheren Younes, M.D. (see Authors page)

Revised: 27 January 2017, last major update August 2014

Copyright: (c) 2014-2017,, Inc.

PubMed Search: postoperative spindle cell thyroid
Cite this page: Postoperative spindle cell nodule. website. Accessed October 22nd, 2018.
Definition / general
Clinical features
  • Thyroid mass
  • History of surgery or FNA
Radiology description
Case reports
Microscopic (histologic) description
  • Spindle cell proliferation
  • Bland cytology, no pleomorphism
  • Low mitotic count, no atypical mitoses
  • Other features may be seen as scattered inflammatory cells and histiocytes, focal myxoid change and delicate blood vessels
Microscopic (histologic) images

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Gross and microscopic findings


Cytology description
  • Spindle cells with histiocytes, vague granulomatous pattern
Cytology images

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Fragments of fibrocollagenous tissue

Positive stains
Electron microscopy description
  • Characteristic myofibroblastic features
Differential diagnosis