Thyroid gland
Papillary carcinoma
Papillary carcinoma in children

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 31 January 2017, last major update March 2009

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: pediatric papillary thyroid carcinoma
Cite this page: Papillary carcinoma in children. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidptdchildren.html. Accessed March 28th, 2017.
Definition / General
  • Children present with more advanced disease than adults, but have better prognosis (Hormones (Athens) 2007;6:200, eMedicine)
  • Regional nodal metastases occur in 60 - 80%, distant metastases in 10 - 20% at diagnosis, often lung
  • Risk factors: family history, prior radiation exposure
Prognostic Factors
Case Reports
Molecular / Cytogenetics Description
  • RET rearrangements more common than adults, BRAF activation less common (20% versus 77% in adults, Mod Pathol 2005;18:898)