Thyroid gland
Papillary carcinoma
Papillary carcinoma in children

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 31 January 2017, last major update March 2009

Copyright: (c) 2003-2017,, Inc.

PubMed Search: pediatric papillary thyroid carcinoma
Cite this page: Papillary carcinoma in children. website. Accessed May 21st, 2018.
Definition / general
  • Children present with more advanced disease than adults, but have better prognosis (Hormones (Athens) 2007;6:200, eMedicine)
  • Regional nodal metastases occur in 60 - 80%, distant metastases in 10 - 20% at diagnosis, often lung
  • Risk factors: family history, prior radiation exposure
Prognostic factors
Case reports
Molecular / cytogenetics description
  • RET rearrangements more common than adults, BRAF activation less common (20% versus 77% in adults, Mod Pathol 2005;18:898)