Thyroid gland
Thyroiditis
Silent thyroiditis



Topic Completed: 1 March 2009

Revised: 18 March 2019

Copyright: 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: silent thyroiditis

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Silent thyroiditis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidsilentthyroiditis.html. Accessed October 21st, 2019.
Definition / general
  • Transient, painless hyperthyroidism that spontaneously resolves
Terminology
  • Also called painless or sometimes chronic lymphocytic thyroiditis
Epidemiology
  • Relatively uncommon; usually women
Etiology
  • Cause unknown, although hyperfunction is due to destruction of thyroid follicles
Clinical features
Laboratory
  • Elevated T3 / T4, low radioactive iodine uptake
Case reports
Treatment
  • Usually none, beta blockers possibly in hyperthyroid phase
Gross description
  • Diffuse goiter or slightly enlarged thyroid gland
Microscopic (histologic) description
  • Preserved lobular pattern with follicular destruction, variable lymphocytic infiltrate, rare / no oncocytic change, no / focal fibrosis
  • T cells present in paracortex, B cells predominate in germinal center
Microscopic (histologic) images

Images hosted on other servers:

Mild lymphocytic infiltrate (Fig 1b)

Differential diagnosis
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