Solitary thyroid nodule
Reviewer: Shahidul Islam, M.D., Ph.D. (see Reviewers page)
Revised: 3 April 2013, last major update March 2009
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Up to 5% are malignant
- Single and cold (on nuclear scan) nodules are risk factors for malignancy, but 80-90% will be benign; other risk factors are radiation to head and neck, rapidly enlarging nodule, ipsilateral adenopathy, male patient, age < 20 years or > 70 years
- Cysts may represent cystic degeneration of follicular adenoma or portions of multinodular goiters
- Present in 2-4% of adults in US, up to 50% of elderly
- Usually women
- Nodules may form due to differential growth of follicular epithelium, with associated secondary changes in neighboring follicles
End of Thyroid gland > Benign neoplasms > Solitary thyroid nodule
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