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Thyroid gland
Papillary carcinoma
Tall cell variant

Reviewer: Shahidul Islam, M.D., Ph.D. (see Reviewers page)
Revised: 12 June 2013, last major update March 2009
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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Clinical features
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Prognostic factors
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Case reports
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Gross description
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Micro description
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Micro images
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Papillary tumor of tall columnar cells
Columnar cell type (top) versus tall cell type (bottom)
“Frosted glass core” appearance
RET staining
Collision tumor with Hürthle cell carcinoma
Images from AFIP:
Abundant acidophilic cytoplasm
Tall epithelial cells
Cytology description
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Cytology images
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Some cells are elongated with cytoplasmic tails
Metastasis to pancreas
Left: nuclear groove (long arrow) and intranuclear inclusion (short arrow); right: intranuclear inclusion (arrow)

Cell block shows papillary cluster of tall
tumor cells with abundant oncocytic cytoplasm
Positive stains
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Molecular / cytogenetics description
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End of Thyroid gland > Papillary carcinoma > Tall cell variant


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