Thyroid gland
Other malignancies
Teratoma




Topic Completed: 1 July 2015

Revised: 18 March 2019

Copyright: 2015-2017, PathologyOutlines.com, Inc.

PubMed Search: teratoma thyroid
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Cite this page: Younes S. Teratoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/thyroidteratomas.html. Accessed May 23rd, 2019.
Definition / general
  • Teratoma is a germ cell tumor characterized by the presence of 3 germ cell layers: ectoderm, endoderm and mesoderm
  • Common in newborns and infants (usually benign), rare in adolescence, usually malignant in adults (Cancer 2000;88:1149)
Sites
Clinical features
  • Thyroid mass, usually normal thyroid function
Radiology images

Images hosted on other servers:

Heterogeneously hypoechoic nodule

Large cystic fat-containing mass

Case reports
Gross description
  • Usually cystic
Gross images

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Well encapsulated, mixed solid and cystic mass

Lymph node involvement

Microscopic (histologic) description
  • Neuro / ectodermal tissue: squamous epithelium, glial tissue
  • Endodermal tissue: GI epithelium, thyroid and salivary glands
  • Mesodermal tissue: bone and cartilage
  • Presence of immature tissue or neuroepithelium makes it a malignant immature teratoma (Am J Surg Pathol 2005;29:700)
Microscopic (histologic) images

Images hosted on PathOut server:

Newborn infant (AFIP)



Images hosted on other servers:

Benign thyroid teratoma

Cartilage

Primitive neuroepithelial cells

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