Trachea - MALT lymphoma

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Trachea

Tumors

MALT lymphoma

Reviewer: Adriana Handra-Luca, M.D. (see Reviewers page)
Revised: 8 February 2013, last major update October 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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● Low grade lymphoma similar to tumors elsewhere (see Lymphoma and plasma cell neoplasms chapter)
● May represent recurrence of parotid tumor, be associated with bronchial tumors
● Polypoid or multiple tumors
● Symptoms: cough, dyspnea, hoarseness, weight loss

Case reports
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● 44 year old woman treated with long term survival (Thorax 2005;60:82)
● 44 year old woman (Intern Med 1992;31:655)
● 62 year old woman with Sjogren syndrome (Nihon Kokyuki Gakkai Zasshi 2011;49:543)
● 71 year old woman (Sao Paulo Med J 2012;130:126 )
● 74 year old woman with laser photoresection (Intern Med 1999;38:276)
● 83 year old woman (Yonsei Med J 2008;49:860)
● Early case with severe upper airway obstruction (Am J Surg Pathol 1992;16:71)

Treatment
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● Bronchoscopic resection, R-COP

Micro description
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● Diffuse infiltrate of small lymphocytes with centrocyte-like features surrounding reactive follicles
● Plasmacytoid cells and lymphoepithelial lesions present

Micro images
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71 year old woman with a history of dry coughing and dyspnea

83 year old woman with a dry cough and dyspnea

Positive stains
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● Light chain restriction

Negative stains
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● CD5, CD10

End of Trachea > Tumors > MALT lymphoma

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