Mucoepidermoid carcinoma

Topic Completed: 1 October 2012

Revised: 5 April 2019

Copyright: 2002-2017,, Inc.

PubMed Search: Mucoepidermoid carcinoma trachea

Adriana Handra-Luca, M.D.
Page views in 2018: 182
Page views in 2019 to date: 125
Cite this page: Handra-Luca A. Mucoepidermoid carcinoma. website. Accessed June 20th, 2019.
Definition / general
  • Usually low grade lesion with squamous cells without atypia in desmoplastic stroma
Clinical features
  • Usually children with a luminal polyp, possibly with bronchus extension
  • May occur in patients with tracheobronchopathia osteochondroplastica
  • Symptoms: dyspnea, stridor
Case reports
  • Resection
Microscopic (histologic) description
  • Low grade lesion with foci of squamous differentiation without atypia in desmoplastic stroma
  • Prominent vascular component
  • No marked atypia, no necrosis, no mitotic activity, no angiolymphatic invasion, may be dedifferentiated
Microscopic (histologic) images

Images hosted on other servers:

Oncocytic tumor:
simple cysts, oncocytes and
antimitochondrial antibody

Positive stains
  • Keratin (entire tumor)
  • Oncocytic tumor: PTAH and antimitochondrial antibody in oncocytes
Negative stains
Differential diagnosis
  • Carcinoid tumor
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