Mucoepidermoid carcinoma

Author: Adriana Handra-Luca, M.D. (see Authors page)

Revised: 16 November 2017, last major update October 2012

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Mucoepidermoid carcinoma trachea

Cite this page: Handra-Luca, A. Mucoepidermoid carcinoma. website. Accessed October 16th, 2018.
Definition / general
  • Usually low grade lesion with squamous cells without atypia in desmoplastic stroma
Clinical features
  • Usually children with a luminal polyp, possibly with bronchus extension
  • May occur in patients with tracheobronchopathia osteochondroplastica
  • Symptoms: dyspnea, stridor
Case reports
  • Resection
Microscopic (histologic) description
  • Low grade lesion with foci of squamous differentiation without atypia in desmoplastic stroma
  • Prominent vascular component
  • No marked atypia, no necrosis, no mitotic activity, no angiolymphatic invasion, may be dedifferentiated
Microscopic (histologic) images

Images hosted on other servers:

Oncocytic tumor:
simple cysts, oncocytes and
antimitochondrial antibody

Positive stains
  • Keratin (entire tumor)
  • Oncocytic tumor: PTAH and antimitochondrial antibody in oncocytes
Negative stains
Differential diagnosis
  • Carcinoid tumor