Table of Contents
Definition / general | Treatment | Gross description | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Handra-Luca A. Mucous membrane plasmacytosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/tracheamucousmembraneplasma.html. Accessed April 21st, 2019.
Definition / general
- Nonneoplastic proliferative disorder of plasma cells
- Mean 54 years, range 40 - 67 years, 2/3 men
Treatment
- Unknown: antibiotics, steroids, surgery are unsuccessful
Gross description
- Cobblestone or warty appearance of larynx, pharynx, palate, lips, mouth, tongue, trachea
Microscopic (histologic) description
- Psoriasiform epithelial hyperplasia with dyskeratosis and dense subepithelial plasmacytosis
- Diffuse but mature plasma cells are polyclonal (i.e. no light chain restriction)
Microscopic (histologic) images
Images hosted on other servers:
Buccal mucosa: hyperplastic, parakeratinized
stratified squamous epithelium with
dense infiltrate of mature
plasma cells in lamina propria
Buccal mucosa: plasma
cells are IgG+, CD138+,
both kappa+ and lambda+
