Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Trachea

Non-neoplastic lesions

Mucous membrane plasmacytosis


Reviewer: Adriana Handra-Luca, M.D. (see Reviewers page)
Revised: 4 February 2013, last major update October 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
=========================================================================

● Non-neoplastic proliferative disorder of plasma cells
● Mean 54 years, range 40-67 years, 2/3 men

Treatment
=========================================================================

● Unknown: antibiotics, steroids, surgery are unsuccessful

Gross description
=========================================================================

● Cobblestone or warty appearance of larynx, pharynx, palate, lips, mouth, tongue, trachea

Micro description
=========================================================================

● Psoriasiform epithelial hyperplasia with dyskeratosis and dense subepithelial plasmacytosis
● Diffuse but mature plasma cells are polyclonal (i.e. no light chain restriction)

Micro images
=========================================================================



Buccal mucosa: hyperplastic, parakeratinized stratified squamous epithelium with dense infiltrate of mature plasma cells in lamina propria


Buccal mucosa: plasma cells are IgG+, CD138+, both kappa+ and lambda+

End of Trachea > Non-neoplastic lesions > Mucous membrane plasmacytosis


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).