Transfusion medicine
Transfusion transmitted disease
Trypanosoma cruzi (Chagas disease)


Topic Completed: 1 October 2011

Revised: 8 April 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Trypanosoma cruzi transfusion [title]
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Cite this page: Pham HP Trypanosoma cruzi - Chagas disease). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/transfusionmedTrypanosomacruzi.html. Accessed April 25th, 2019.
Definition / general
  • Chagas disease is confined mainly to Mexico and South America
  • 50,000 - 100,000 chronic carriers in U.S., due to immigration
  • Transmitted to humans through bite of reduviid bugs
  • Canada to start screening in 2008 (CMAJ 2007;177:242)
  • FDA licensed a screening test for antibodies to T. cruzi in blood donors in 2006; Red Cross and other blood collection centers are screening in U.S.
  • Photoinactivation may be useful for red cell suspensions (Transfus Apher Sci 2007;37:23), platelets (Transfusion 2007;47:434) or plasma (Vox Sang 2006;91:285)

Donor / control positive rates:
Case reports
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