Transfusion medicine
Transfusion transmitted disease
Trypanosoma cruzi (Chagas disease)

Author: Huy Phu Pham, M.D. (see Authors page)

Revised: 2 November 2017, last major update October 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Trypanosoma cruzi transfusion [title]

Cite this page: Pham, H.P. Trypanosoma cruzi - Chagas disease). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/transfusionmedTrypanosomacruzi.html. Accessed November 20th, 2017.
Definition / general
  • Chagas disease is confined mainly to Mexico and South America
  • 50,000 - 100,000 chronic carriers in U.S., due to immigration
  • Transmitted to humans through bite of reduviid bugs
  • Canada to start screening in 2008 (CMAJ 2007;177:242)
  • FDA licensed a screening test for antibodies to T. cruzi in blood donors in 2006; Red Cross and other blood collection centers are screening in U.S.
  • Photoinactivation may be useful for red cell suspensions (Transfus Apher Sci 2007;37:23), platelets (Transfusion 2007;47:434) or plasma (Vox Sang 2006;91:285)

Donor / control positive rates:
Case reports