Transfusion medicine
Transfusion transmitted disease
Bacterial contamination in pRBC products




Topic Completed: 1 September 2011

Revised: 5 April 2019

Copyright: 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: pRBC bacterial contamination
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Cite this page: Pham H. Bacterial contamination in pRBC products . PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/transfusionmedbacteriaprbc.html. Accessed April 18th, 2019.
Definition / general
  • Rate of bacterial contamination in packed RBCs (pRBCs) is 2.6 in 100,000 pRBCs transfused and the rate of septic transfusion reaction is 1 in 250,000 products
  • Risk of death is 1 per 8 million units
  • Most bacteria is not viable at storage temperature
  • Associated with high mortality rate
  • Yersinia enterocolitica is responsible for 60% of reported cases of RBC associated sepsis; 70% are fatal
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