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Transfusion medicine

Tranfusion-transmitted disease

Bacterial contamination in pRBC products

Reviewer: Huy Phu Pham, M.D. (see Reviewers page)
Revised: 31 October 2011, last major update September 2011
Copyright: (c) 2007-2011, PathologyOutlines.com, Inc.


● Rate of bacterial contamination in packed RBC's (pRBCs) is 2.6 in 100,000 pRBCs transfused, and the rate of septic transfusion reaction is 1 in 250,000 products
● Risk of death is 1 per 8 million units
● Most bacteria is not viable at storage temperature
● Associated with high mortality rate
Yersinia enterocolitica is responsible for 60% of reported cases of RBC-associated sepsis; 70% are fatal

Case reports

Yersinia enterocolitica (Arch Pathol Lab Med 1996;120:499, J Clin Microbiol 2000;38:2788, Transfusion 2005;45:814)

End of Transfusion Medicine > Tranfusion-transmitted disease > Bacterial contamination of transfusions > Bacterial contamination in pRBC products

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