Transfusion medicine
Tranfusion side effects
Hemoglobinopathy (apparent) due to transfusion

Author: Huy Phu Pham, M.D. (see Authors page)

Revised: 25 October 2017, last major update September 2011

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Transfusion side effects hemoglobinopathy apparent

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Cite this page: Pham, H.P. Hemoglobinopathy (apparent) due to transfusion. website. Accessed January 22nd, 2019.
Definition / general
  • Due to donor blood with a hemoglobinopathy, most commonly hemoglobin C
  • Abnormal hemoglobin ranges from 1 - 14% of recipient hemoglobin; recipient often has received multiple transfusions (Arch Pathol Lab Med 2006;130:1830)
  • Important to identify to avoid unnecessary testing and treatment; must also notify the donor
  • Important to send untransfused sample to test for hemoglobinopathy or red cell enzymatic defects
  • Detection of hemoglobinopathies may rarely be suppressed by transfusions (Arch Pathol Lab Med 2005;129:e107)
  • See also transfusion associated microchimerism
Case reports