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Ureters

Endometriosis


Reviewers: Sean Williamson, M.D. (see Reviewers page)
Revised: 2 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

General
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● Rare in ureter, but can result in renal failure due to silent obstruction
● Associated with hydroureter/hydronephrosis
● Tendency to involve distal third of left ureter (Hum Pathol 2008;39:954)
● Extrinsic involving serosal or peritoneal surface (adventitia or connective tissue)
● Intrinsic involving muscularis propria, lamina propria, lumen
● Rarely malignant transformation or endometrial hyperplasia can be present

Case reports
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● 51 year old woman with endometrioid adenocarcinoma arising in ureteral endometriosis (Scientific World Journal 2010;10:1714)

Micro description
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● Similar to endometriosis seen elsewhere, diagnosis based on the presence of endometrial glands (usually inactive or proliferative pattern) with endometrial stroma (usually normal-appearing), sometimes restricted to a thin zone around the glandular component
● Foamy or hemosiderin-laden macrophages
● Sometimes a fibrotic reaction

Micro images
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Endometrial glands and stroma involving the adjacent soft tissue

Positive stains
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● ER, PR, CK7, CA-125, CD10 (stroma) (Hum Pathol 2008;39:954)

End of Ureters > Endometriosis


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