Urethra
General
Staging - urethral carcinoma

Author: Turki Al-Hussain, M.D. (see Authors page)

Revised: 9 November 2017, last major update June 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Staging urethral carcinoma [title]

Cite this page: Al-Hussain, T. Staging - urethral carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/urethrastaging.html. Accessed December 13th, 2017.
Definition / general
Changes from AJCC 6th to 7th edition:
  • For urothelial carcinoma of prostate, T1 is defined as tumors invading subepithelial connective tissue
Primary tumor (T) (male and female)
  • TX: Primary tumor cannot be assessed
  • T0: No evidence of primary tumor
  • Ta: Noninvasive papillary, polypoid or verrucous carcinoma
  • Tis: Carcinoma in situ
  • T1: Tumor invades subepithelial connective tissue
  • T2: Tumor invades any of the following: corpus spongiosum, prostate or periurethral muscle
  • T3: Tumor invades any of the following: corpus cavernosum, beyond prostatic capsule, anterior vagina or bladder neck
  • T4: Tumor invades other adjacent organs
Urothelial (transitional) carcinoma of prostate
  • Tis pu: Carcinoma in situ, involvement of prostatic urethra
  • Tis pd: Carcinoma in situ, involvement of prostatic ducts
  • T1: Tumor invades urethral subepithelial connective tissue
  • T2: Tumor invades any of the following: corpus spongiosum, prostatic stroma or periurethral muscle
  • T3: Tumor invades any of the following: corpus cavernosum, beyond prostatic capsule, bladder neck (extraprostatic extension)
  • T4: Tumor invades other adjacent organs
Regional lymph nodes (N)
  • NX: Regional lymph nodes cannot be assessed
  • N0: No regional lymph node metastasis
  • N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension
  • N2: Metastasis in a single lymph node more than 2 cm in greatest dimension or in multiple nodes
Distant metastasis (M)
  • M0: No distant metastasis
  • M1: Distant metastasis
Stage grouping
  • Stage 0a:
  • Ta N0 M0
  • Stage 0is:
  • Tis N0 M0 or Tis pu N0 M0 or Tis pd N0 M0
  • Stage I:
  • T1 N0 M0
  • Stage II:
  • T2 N0 M0
  • Stage III:
  • T1 - T2 N1 M0 T3 N0 - N1 M0
  • Stage IV:
  • T4 or N2 or M1