Urethra - Staging - urethral carcinoma

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Urethra

Staging - urethral carcinoma

Reviewers: Turki Al-Hussain, M.D. (see Reviewers page)
Revised: 3 June 2012, last major update June 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

General
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Changes from AJCC 6th to 7th edition:
● For urothelial carcinoma of prostate, T1 is defined as tumors invading subepithelial connective tissue

Primary tumor (T) (male and female)
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● TX: Primary tumor cannot be assessed
● T0: No evidence of primary tumor
● Ta: Noninvasive papillary, polypoid or verrucous carcinoma
● Tis: Carcinoma in situ
● T1: Tumor invades subepithelial connective tissue
● T2: Tumor invades any of the following: corpus spongiosum, prostate or periurethral muscle
● T3: Tumor invades any of the following: corpus cavernosum, beyond prostatic capsule, anterior vagina or bladder neck
● T4: Tumor invades other adjacent organs

Urothelial (transitional) carcinoma of prostate
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● Tis pu: Carcinoma in situ, involvement of prostatic urethra
● Tis pd: Carcinoma in situ, involvement of prostatic ducts
● T1: Tumor invades urethral subepithelial connective tissue
● T2: Tumor invades any of the following: corpus spongiosum, prostatic stroma or periurethral muscle
● T3: Ttumor invades any of the following: corpus cavernosum, beyond prostatic capsule, bladder neck (extraprostatic extension)
● T4: Tumor invades other adjacent organs (invasion of bladder)

Regional lymph nodes (N)
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● NX: Regional lymph nodes cannot be assessed
● N0: No regional lymph node metastasis
● N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension
● N2: Metastasis in a single lymph node more than 2 cm in greatest dimension, or in multiple nodes

Distant Metastasis (M)
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● M0: No distant metastasis
● M1: Distant metastasis

Stage grouping
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● Stage 0a: Ta N0 M0
● Stage 0is: Tis N0 M0 or Tis pu N0 M0 or Tis pd N0 M0
● Stage I: T1 N0 M0
● Stage II: T2 N0 M0
● Stage III: T1-T2 N1 M0, T3 N0-N1 M0
● Stage IV: T4 or N2 or M1

End of Urethra > Staging - urethral carcinoma

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