Stromal tumors
Uterine tumors resembling ovarian sex cord tumors

Author: Nat Pernick, M.D. (see Authors page)

Revised: 3 February 2017, last major update October 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed search: uterine tumors resembling ovarian sex cord tumors

Cite this page: Uterine tumors resembling ovarian sex cord tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uterusUTROSCT.html. Accessed February 22nd, 2017.
Definition / General
  • Rare tumors of uncertain etiology
  • Most are benign with uniform cells, no infiltration and low mitotic index
  • Malignant variants behave similar to low grade stromal sarcoma (may recur or metastasize)
Case Reports
  • 62 year old woman with recurrent postmenopausal bleeding and uterine polyp (Cases J 2009;2:55)
Micro Description
  • More cellular than endometrial stromal nodules, mature smooth muscle often present
  • Sex cord-like elements are cords, tubules or sheets resembling epithelial cells, but with scanty cytoplasm, indistinct cell margins and round nuclei
  • May have abundant eosinophilic or clear cytoplasm
  • No prominent arterioles
Micro Images

Images hosted on other servers:

Various images

Tumor cells resemble granulosa cells

Various images

Positive Stains
Negative Stains
Electron Microscopy Description
  • Polyphenotypic neoplasms with focal epithelial and variable sex cord-like differentiation, but no smooth muscle differentiation (Ultrastruct Pathol 2010;34:16)
Differential Diagnosis