Dyssynchronous endometrium

Author: Nat Pernick, M.D. (see Authors page)

Revised: 14 August 2018, last major update December 2011

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed search: dyssynchronous endometrium

Page views in 2018: 4,553
Page views in 2019 to date: 226
Cite this page: Pernick, N. Dyssynchronous endometrium. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uterusdyssynchronous.html. Accessed January 21st, 2019.
Definition / general
  • Discordance between glands and stroma, both usually in secretory phasel
  • Also defined as endometrial glandular dating lagging both chronological and stromal dating by 3+ days
  • Also proliferative endometrium and secretory stroma
  • Often due to dysfunctional uterine bleeding (DUB)
  • DUB patients lack cyclic endometrial stimulation; instead have constant unopposed estrogen production with continuous endometrial stimulation; endometrium outgrows its blood supply, leading to tissue breakdown and sloughing
  • Healing of this endometrium is irregular and dyssynchronous (eMedicine)
Microscopic (histologic) images

Images hosted on other servers:

Dyssynchronous endometrium