Endometrial carcinoma
Glassy cell carcinoma

Topic Completed: 1 September 2011

Revised: 25 February 2019

Copyright: 2002-2017, PathologyOutlines.com, Inc.

PubMed search: glassy cell carcinoma

Nat Pernick, M.D.
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Cite this page: Pernick N. Glassy cell carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uterusglassycell.html. Accessed August 24th, 2019.
Definition / general
  • Rare type of adenosquamous carcinoma, similar to cervical counterpart
  • See also topic in Cervix chapter
Case reports
Microscopic (histologic) description
  • Diffuse solid sheets of tumor cells with eosinophilic, ground glass cytoplasm, distinct cell walls, large nuclei and prominent nucleoli
  • Frequent mitotic figures
  • Heavy eosinophilic and lymphocytic infiltrate common
  • Usually some glandular component
  • Most authors require 30% - 100% of glassy cells for diagnosis
Microscopic (histologic) images

Images hosted on other servers:

Various images

Various images - cervix

Positive stains
Positive stains
Electron microscopy description
  • Intermediate filaments, polyribosomes, tonofibrils and desmosomes
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