Endometrial carcinoma
Glassy cell carcinoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 January 2017, last major update September 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed search: glassy cell carcinoma

Cite this page: Glassy cell carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uterusglassycell.html. Accessed October 17th, 2018.
Definition / general
  • Rare type of adenosquamous carcinoma, similar to cervical counterpart
  • See also topic in Cervix chapter
Case reports
Microscopic (histologic) description
  • Diffuse solid sheets of tumor cells with eosinophilic, ground glass cytoplasm, distinct cell walls, large nuclei and prominent nucleoli
  • Frequent mitotic figures
  • Heavy eosinophilic and lymphocytic infiltrate common
  • Usually some glandular component
  • Most authors require 30% - 100% of glassy cells for diagnosis
Microscopic (histologic) images

Images hosted on other servers:

Various images

Various images - cervix

Positive stains
Positive stains
Electron microscopy description
  • Intermediate filaments, polyribosomes, tonofibrils and desmosomes