Stromal tumors

Author: Nat Pernick, M.D. (see Authors page)

Revised: 9 February 2017, last major update August 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed search: lipoleiomyoma [title] uterus

Related topics: leiomyoma

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Cite this page: Lipoleiomyoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uterusleiomyomalipo.html. Accessed November 12th, 2019.
Definition / general
  • 2% of all leiomyomas; combination of leiomyoma and mature adipocytes with benign behavior (Int J Gynecol Pathol 2006;25:239)
  • Also includes neoplasms composed entirely of mature adipocytes
  • May be due to adipose metaplasia in leiomyomas; does not appear to be degenerative, since adipose tissue has low proliferative activity by Ki67 staining
  • May give rise to liposarcoma (Am J Surg Pathol 2011;35:221)
Case reports
Gross images

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Pale yellow to bright yellow appearance

Intramural yellow tumor

Microscopic (histologic) images

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Various images

With chondroid metaplasia

Positive stains
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