Leukemia / lymphoma
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 12 November 2011, last major update November 2011
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● Rare to be involved by non-Hodgkin’s lymphoma; rarer still to arise as primary tumor in uterus (Aust NZ J Obstet Gynaecol 2011 Sep 19 [Epub ahead of print])
● More common (7%) to be involved by CLL
● Large cell lymphoma and granulocytic sarcoma resemble endometrial stromal sarcoma
● Low grade endometrial lymphomas are rare (Am J Surg Pathol 1997;21:187)
● Both low and high stage have similar mean age (55 vs. 58 years), present with abnormal uterine bleeding, usually diffuse large B cell subtype (Mod Pathol 2000;13:19)
● Low stage tumors: usually involve cervix, 5 year survival 83%
● High stage tumors: usually involve uterine corpus, 5 year survival 29%
● 30 year old woman with AML and relapse in uterus (Yonsei Med J 2004;45:330)
● 38 year old woman with pre-T ALL (Ann Diagn Pathol 2002;6:125)
● 48 year old woman with primary NK-Cell lymphoma, nasal-type (Pathol Oncol Res 2011 Jan 28 [Epub ahead of print])
● 71 year old woman with intravascular lymphoma (Int J Surg Pathol 2009 Nov 30 [Epub ahead of print])
● 76 year old woman with rectovaginal pressure and lymphoproliferative process on cervical cone biopsy (J Low Genit Tract Dis 2010;14:63)
Various images of lymphomas
End of Uterus > Other tumors > Leukemia / lymphoma
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