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Non tumor


Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 19 February 2012, last major update February 2012
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

● Also known as glandular and stroma breakdown
● Common in perimenopausal women
Micro: condensation of endometrial stroma under surface endometrium and nuclear dust; associated with predecidualized stroma and glandular exhaustion; cannot assess architectural changes; may see signet ring cells (benign) if prolonged shedding
Differential diagnosis: small cell carcinoma

Dyssynchronous endometrium

Weakly proliferative endometrium:
● Normal in prepubertal girls, perimenopausal or menopausal women
● Proliferative glands (columnar or cuboidal epithelium with pseudostratification, elongated and densely basophilic nuclei), but relatively reduced number of mitotic figures
● Glands usually tubular or cystic, may be closely packed
● Stroma also appears inactive with variable collagenization and minimal mitotic activity

Micro images

End of Uterus > Non tumor > Miscellaneous

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