Stromal tumors
Postoperative spindle cell tumors

Topic Completed: 1 October 2011

Revised: 25 February 2019

Copyright: 2002-2017, PathologyOutlines.com, Inc.

PubMed search: postoperative "spindle cell" tumors

Mohamed Mokhtar Desouki, M.D., Ph.D.
Page views in 2018: 441
Page views in 2019 to date: 357
Cite this page: Desouki M. Postoperative spindle cell tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/uteruspostop.html. Accessed September 23rd, 2019.
Definition / general
  • Postoperative spindle cell nodule
  • Post procedural, e.g. dilatation and curettage
  • Reparative proliferations of fibroblastic cells in response to an inciting factor
Clinical features
  • Vaginal bleeding
Prognostic factors
  • No recurrence reported even after incomplete excision
Case reports
Microscopic (histologic) description
  • Dense cellular proliferation of mitotically active spindle cells which have elongated nuclei with evenly dispersed chromatin and abundant eosinophilic cytoplasm
  • Marked vascularity with extravasated RBCs and hemosiderin
  • Mitotic rate is often high, but abnormal mitoses or atypia are absent
Microscopic (histologic) images

Images hosted on other servers:

Bladder tumor

Negative stains
Differential diagnosis
  • Sarcoma NOS: Marked nuclear anaplasia, variable pleomorphism, 20+ mitotic figures/10 HPF; extensive necrosis is common
  • Sarcomatoid carcinoma / MMMT: biphasic with sarcomatoid and carcinomatous elements; angiolymphatic invasion common; keratin+
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