Benign tumors
Fibroepithelial (stromal) polyp

Topic Completed: 1 April 2014

Revised: 25 February 2019

Copyright: 2002-2017,, Inc.

PubMed Search: Fibroepithelial polyp vagina

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Cite this page: Mansouri J. Fibroepithelial (stromal) polyp. website. Accessed October 21st, 2019.
Definition / general
  • Polyp composed of a central core of fibrous tissue containing irregular shaped thin walled vessels and stellate cells
  • Overlying squamous epithelium may display reactive changes but without papillomatous architecture or koilocytosis
  • Adult women during pregnancy or neonates
  • Vagina, vulva
  • Due to hormone induced hyperplasia of loose subepithelial connective tissue or end stage of granulation tissue (J Clin Pathol 1992;45:235)
Prognostic factors
  • Benign, may recur during pregnancy
Case reports
  • Local excision
Gross description
  • Polypoid, multilobulated and usually solitary
Microscopic (histologic) description
  • Central fibrovascular core covered by normal appearing squamous epithelium without intervening Grenz zone
  • Stroma may be edematous, hypocellular or myxoid
  • May have atypical stromal cells including stellate and multinucleated cells
Microscopic (histologic) images

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Low power

Myxoid stroma and blood vessels

Squamous epithelium is focally thickened

Positive stains
Negative stains
Differential diagnosis
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