Benign tumors
Superficial cervicovaginal myofibroblastoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 September 2017, last major update March 2003

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Superficial cervicovaginal myofibroblastoma

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Cite this page: Pernick, N. Superficial cervicovaginal myofibroblastoma. website. Accessed January 23rd, 2019.
Definition / general
  • Mean age 58 years, range 40 to 74 years
  • Benign behavior
  • May be neoplastic proliferation of hormonally responsive mesenchymal cells native to subepithelial stroma of endocervix, vulva and vagina of adult women
Gross description
  • Well circumscribed, polypoid or nodular mass, mean 3 cm (range 1 to 6.5 cm) arising in the superficial lamina propria of cervix and vagina
Microscopic (histologic) description
  • Cellular, composed of bland spindled and stellate mesenchymal cells in collagenous stroma with myxoid and edematous foci
  • Often lace-like pattern in hypocellular area, vague fascicular growth pattern in cellular area
  • Minimal mitotic activity
  • No atypical mitotic figures
Negative stains
Additional references