Benign tumors
Spindle cell epithelioma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 September 2017, last major update March 2003

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Spindle cell epithelioma vagina

Cite this page: Pernick, N. Spindle cell epithelioma. website. Accessed August 19th, 2018.
Definition / general
  • Aka benign mixed tumor but does not appear to derive from myoepithelial cells
  • Near hymeneal ring
  • May recur locally
Gross description
  • Well circumscribed but not encapsulated, not connected to surface epithelium
Microscopic (histologic) description
  • Small, stromal type spindle cells mixed with squamous cells and mucinous glands
  • Numerous small vessels and localized hyaline globules
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
Negative stains
Electron microscopy description
  • Epithelial differentiation (tonofilaments and desmosomes), no myoepithelial differentiation