Urothelial (transitional) metaplasia

Author: Nat Pernick, M.D. (see Authors page)

Revised: 21 September 2017, last major update March 2003

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Urothelial (transitional) metaplasia

Cite this page: Pernick, N. Urothelial (transitional) metaplasia. website. Accessed August 19th, 2018.
Definition / general
  • Mean age 68 years (range 50 to 84 years); usually no hormonal therapy; incidental microscopic finding
Microscopic (histologic) description
  • Hyperplastic epithelium lacking maturation, composed of spindled nuclei with longitudinal nuclear grooves, perinuclear halos, low N/C ratios, rare / no mitotic figures
  • Usually no atypia
Differential diagnosis
Additional references