Malignant tumors
Yolk sac tumor

Topic Completed: 1 March 2003

Revised: 26 February 2019

Copyright: 2003-2015,, Inc.

PubMed Search: Yolk sac tumor vagina

Nat Pernick, M.D.
Page views in 2018: 193
Page views in 2019 to date: 244
Cite this page: Pernick N. Yolk sac tumor. website. Accessed December 11th, 2019.
Definition / general
  • Aka endodermal sinus tumor
  • Girls under age 2, posterior wall of vagina or fornices
  • Simulates botryoid rhabdomyosarcoma clinically
  • Surgery, multidrug chemotherapy, possibly radiation therapy
Positive stains
Negative stains
  • LeuM1
Differential diagnosis
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