Reviewer: Monika Roychowdhury, M.D. (see Reviewers page)
Revised: 10 October 2013, last major update October 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
PubMed Search: Vulva multinucleated atypia
- Histologic pattern of multinucleated keratinocytes in basal and middle layers of squamous epithelium of vulva (Am J Surg Pathol 1994;18:1233)
- May mimic human papillomavirus (HPV)-related squamous dysplasia, but not associated with HPV
- May present as flesh colored vulvar papules
- Multinucleated keratinocytes without significant nuclear atypia in lower to middle epithelial layers of otherwise normal appearing squamous epithelium
- These multinucleated cells may contain 2-10 nuclei, often prominent nucleoli
- No surface atypia, no hyperchromasia, no pleomorphism
- No significant inflammation
End of Vulva > Non-neoplastic disorders > Multinucleated atypia
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com
with any questions (click here for other