Bladder & urothelial tract
General
Staging-female urethra
Last author update: 3 January 2019
Last staff update: 26 January 2024 (update in progress)
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PubMed Search:
Female urethra staging
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Cite this page: Zynger DL. Staging-female urethra. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/vulvaurethrastaging.html. Accessed April 19th, 2024.
Definition / general
- All carcinomas of the female urethra are covered by this staging system
Essential features
- AJCC 7th edition staging was sunset on December 31, 2017; as of January 1, 2018, use of the 8th edition is mandatory
ICD coding
- ICD-10: C68.0 - malignant neoplasm of urethra
Primary tumor (pT)
- pTX: cannot be assessed
- pT0: no evidence of primary tumor
- pTa: noninvasive papillary carcinoma
- pTis: carcinoma in situ
- pT1: invasion of urethral subepithelial connective tissue
- pT2: invasion of periurethral muscle
- pT3: invasion of anterior vagina
- pT4: invasion of adjacent organs (example: bladder wall)
Regional lymph nodes (pN)
- pNX: cannot be assessed
- pN0: no regional lymph node metastasis
- pN1: metastasis in 1 regional lymph node
- pN2: metastasis in greater than 1 regional lymph node
Note:
- Regional lymph nodes include superficial / deep inguinal, perivesical, obturator, internal iliac / hypogastric, external iliac, presacral, sacral NOS, pelvic NOS
Prefixes
- y: preoperative radiotherapy or chemotherapy
- r: recurrent tumor stage
AJCC prognostic stage groups
| Stage 0a: | Ta | N0 | M0
|
| Stage 0is: | Tis | N0 | M0
|
| Stage I: | T1 | N0 | M0
|
| Stage II: | T2 | N0 | M0
|
| Stage III: | T3 | N0 | M0
|
| | T1 - 3 | N1 | M0
|
| Stage IV: | T4 | N0 - 2 | M0 - 1
|
| | TX - 4 | N2 | M0 - 1
|
| | TX - 4 | NX - 2 | M1
|
Registry data collection variables
- Urothelial carcinoma grade (high / low)
- Squamous cell / adenocarcinoma grade (1 - 3)
Histologic grade (G)
- Urothelial carcinoma
- LG: low grade
- HG: high grade
- Squamous cell / adenocarcinoma
- GX: cannot be assessed
- G1: well differentiated
- G2: moderately differentiated
- G3: poorly differentiated
Histopathologic type
- Noninvasive urothelial carcinoma
- Invasive urothelial carcinoma
- Conventional urothelial carcinoma
- Urothelial carcinoma variants
- Squamous cell carcinoma
- Adenocarcinoma (including those arising from periurethral glands)
- Small cell carcinoma
Board review style question #1
A urothelial carcinoma of the female urethra at the deepest point of invasion involves the bladder wall. Which is the correct pT category?
- pT1
- pT2
- pT3
- pT4
Board review style answer #1
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