Nonneoplastic disorders
Vulvar hypertrophy with lymphedema

Topic Completed: 1 October 2013

Minor changes: 27 February 2019

Copyright: 2002-2017,, Inc.

PubMed Search: Vulvar hypertrophy lymphedema

Monika Roychowdhury, M.D.
Page views in 2019: 974
Page views in 2020 to date: 307
Cite this page: Roychowdhury M. Vulvar hypertrophy with lymphedema. website. Accessed June 3rd, 2020.
Clinical features
  • Patient age range 19 - 59 years
  • Present with papillomatous plaques, skin polyps, generalized vulvar enlargement or massive pedunculated masses that had been present for variable durations
Case reports
  • Simple surgical excision with vulvoplasty is curative
Microscopic (histologic) description
  • Stromal edema with hypocellular proliferation of fibroblastic cells, vessels with perivascular collagen deposition, ectatic tortuous lymphatics
  • No true thick walled vessels
  • Other possible findings include multinucleated giant cells, dermal fibrosis, dermal chronic inflammation, perivascular chronic inflammation (superficial or deep), hyperkeratosis, acanthosis and blood vessels of varying calibers
Microscopic (histologic) images

Images hosted on other servers:

Fibroblastic cells in edematous myxoid stroma

Blood vessels with
collagen deposition

Dilated and tortuous lymphatics

Edematous and collagenous dermis

Differential diagnosis
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