Michael Torbenson, Yoh Zen, Matthew M. Yeh

$199 list, ARP (2018)

Posted December 20, 2018

Series: AFIP Tumor 4th edition

Listed under: liver

Numerous advances in our understanding of the pathology and molecular features of liver tumors have been made since the publication of the Third Series Fascicle, Tumors of the Liver and Intrahepatic Bile Ducts, nearly two decades ago. Examples of recent advances include the identification of novel entities, including their precursor lesions, the discovery of key molecular changes, including the fusion transcript between the DNAJB1 gene and the PRKACA gene in fibrolamellar carcinoma, the use of glutamine synthetase in the diagnosis of focal nodular hyperplasia, and the subtyping of hepatocellular adenomas using molecular and immunohistochemical methods. Together with the more unified classification and terminology of intrahepatic bile duct tumors and their precursors, these advances call for updated information that is presented in this volume.

Elizabeth Montgomery, Rhonda K. Yantiss, Dale C. Snover, Laura H. Tang

$199 list, ARP (2017)

Posted December 20, 2018

Series: AFIP Tumor 4th edition

Listed under: GI

There have been many advances in the pathology of intestinal tumors since the publication of the Third Series Intestines Fascicle in 2003, but many of the foundations of intestinal tumor diagnosis remain tried and true. Tubular adenomas are still tubular adenomas, but better understanding of serrated polyps has been a key advance in the years since the publication of the Third Series volume. Additionally, developments in molecular biology of colorectal carcinoma have allowed for targeted therapy and refinements to our evaluation of Lynch syndrome, which was termed hereditary nonpolyposis colorectal carcinoma (HNPCC) in the past. Our understanding of other polyposis syndromes has similarly blossomed in the past 15 years. Neuroendocrine tumors have been reclassified in the 2010 World Health Organization classification of gastrointestinal tumors. The molecular basis of gastrointestinal stromal tumors of the intestines has been a subject of great interest as well. In producing this update, this group of authors has enjoyed working together in gathering images and information to update this edition of the Intestines atlas. In doing so, we stand on the shoulders of giants before us, namely Drs. Robert H. Riddell, Robert E. Petras, Geraint T. Williams, and Leslie H. Sobin.

L. Jeffrey Medeiros, Dennis P. O'Malley, Nancy P. Caraway, Francisco Vega, Kojo S. J. Elenitoba-Johnson, Megan S. Lim

$249 list, ARP (2017)

Posted December 20, 2018

Series: AFIP Tumor 4th edition

Listed under: hematopathology; Textbook chapters: Lymph nodes & spleen, nonlymphoma, Hematology

The understanding of diagnostic lymph node and spleen pathology has evolved at an impressive pace since 1995, when the third series AFIP atlas was published. Progress has been fueled, in large part, by the application of a number of technologies to the study of hematopoietic neoplasms. The World Health Organization (WHO) classification scheme for hematologic neoplasms has captured much of this progress, and is generally accepted for clinical practice. The current volume, part of the fourth series of atlases, integrates the WHO classification, including the 2016 revision, and highlights areas in which the WHO classification is likely to evolve with time. In keeping with the goals and tradition of the atlases, this volume emphasizes morphological features of hematopoietic neoplasms, and includes a discussion of differential diagnoses for each disease category. In addition, the results of immunophenotypic and molecular genetic testing for each disease are highlighted, including findings generated by using high-throughput techniques that likely will be integrated into standard diagnostics in the near future.

Allen P. Burke, Fabio R. Tavora, Joseph J. Maleszewski and Aletta Ann Frazier

419 pages, $158 list , ARP (2015)

Posted October 1, 2015

Series: AFIP Tumor 4th edition

Listed under: cardiovascular; Textbook chapters: Heart

Since the publication of the Third Series atlas on heart tumors, there have been several changes in the pathology and classification of these lesions. The current edition updates the status of heart tumors, with emphasis on newer findings, especially molecular advances. In most cases, the authors have followed the classification of the World Health Organization, whose updated volume on tumors of the lung, heart, and mediastinum is forthcoming. Because newer imaging modalities, especially cardiac magnetic resonance imaging and 3-D echocardiography are increasingly utilized in preoperative evaluation of heart tumors, the authors have introduced a chapter devoted exclusively to radiologic diagnosis.

Juan Rosai, Ronald A. DeLellis, Maria Luisa Carcangiu, William J. Frable and Giovanni Tallini

606 pages, $165 list, ARP (2015)

Posted December 31, 2015

Series: AFIP Tumor 4th edition

Listed under: head & neck/endocrine; Textbook chapters: Thyroid & parathyroid glands

In the years since the publication of the Third Series AFIP Fascicles on the thyroid and parathyroid glands, awareness of the remarkable morphologic diversity of thyroid carcinoma has notably expanded, and great advances have been made in unraveling the molecular genetic features of thyroid and parathyroid tumors. There has also been an increased interest in the use of the fine-needle aspiration technique for the diagnosis and management of thyroid tumors, and in the role of the pathologist in the operative handling of the hyperfunctioning parathyroid gland. This Fascicle documents the most significant advances that have taken place in these areas, emphasizing those with a practical application at the clinical level. The format remains similar to that of the previous versions, but the two thyroid and parathyroid Fascicles have been merged into one, and most of the black and white gross photographs and photomicrographs have been replaced with color images. The authors include a number of the most recent references, but have not ignored the classic works in the field, many of which have descriptions, illustrations, and insights that cannot be bettered. This Fascicle fulfills the original goal of this series, which is that of helping the pathologist diagnose and anticipate the behavior of tumors and tumor-like lesions included in this publication.

C.R. Antonescu, B. W. Scheithauer, James M. Woodruff

553 pages, $165 list, ARP (2013)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

Listed under: neuropathology

This edition describes the spectrum of neoplasms, hamartomas, hyperplasias, reactive lesions, and inflammatory pseudotumors arising from or associated with peripheral nerves. Included are lesions affecting spinal nerves and extradural portions of cranial nerves. Specifically excluded from this discussion are lesions of the optic nerve, a central nervous system structure.

Stacey E. Mills, Edward B. Stelow and Jennifer L. Hunt

584 pages, $160 list, ARP (2013)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

The current incarnation of this Fascicle builds on its predecessors and is meant to serve as an up-to-date text-rich atlas of tumors involving the upper aerodiges­tive tract and ear. Emphasis in the current work remains focused on light microscopy, but ancillary diagnostic techniques, including electron microscopy, immunohisto­chemistry, and molecular diagnostics, are presented in detail where appropriate. This volume will undoubtedly serve as an invaluable diagnostic reference for years to come.

Sylvia Asa

283 pages, $95 list, ARP (2011)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

Listed under: neuropathology; Textbook chapters: CNS tumor

The classification of pituitary disease is becoming easier, and as targeted therapies are being developed, the role of the pathologist in determining accurate diagnoses is increasingly important. The surgical pathologist musttherefore recognize the important role of morphologic analysis in classifying sellar pathology for the diagnosis and management of the pituitary patient.

David E. Elder, George F. Murphy

468 pages, $165 list, ARP (2010)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

Listed under: dermatopathology

In surgical pathology practice, distinguishing malignant from benign melanocytic lesions represents one of the major problem areas. Failure to diagnose a malignant melanoma can have catastrophic results, but separating melanomas from their simulants is often difficult, and over-diagnosis of melanoma is also inappropriate. This fascicle presents a comprehensive account of benign and malignant melanocytic lesions. The benign lesions encompass the major simulants of melanoma. In addition, some of them, such as dysplastic nevi, have significance as markers of individuals at increased risk for the development of melanoma. It has become ever more apparent, especially with the recent advent of molecular classification, that melanoma is not one disease, and that prognosis in melanoma can vary considerably from lesions that present minimal risk, to dangerous malignancies at opposite ends of a spectrum. The details of therapy for these lesions are very different and are determined for the most part by their diagnostic and prognostic features as judged by microscopy. This fascicle explains in detail the use of attributes for microstaging and for prediction of prognosis in melanoma, including discussion of the latest AJCC staging system. More importantly, however, it provides a richly illustrated roadmap for diagnosis of the entire spectrum of melanocytic tumors. Discussion of the lesions is firmly grounded in their clinical significance, with detailed descriptions of clinical features often accompanied by clinical images. Lesions in general are illustrated in multiple microscopic images ranging from scanning magnification to high power. Cytologic as well as architectural features are clearly delineated. Pathophysiology, epidemiology, and molecular attributes are also discussed. This work will serve as a comprehensive text for learning on the part of trainees, and also as an invaluable diagnostic reference for more experienced diagnosticians in daily practice.

Yukio Shimosato, Kiyoshi Mukai and Yoshihiro Matsuno

322 pages, $135 list, ARP (2010)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

Listed under: mediastinum/serosa; Textbook chapters: Mediastinum

Since the publication of the AFIP Third Series fascicle in 1997, the World Health Organization (WHO) has printed two major volumes concerning tumors of the thymus. Drs. Mukai and Shimosato, who are not only two of the authors of Tumors of the Mediastinum but also co-authors of the Third Series fascicle, were collaborators on the WHO volumes. In the last 10 years, little progress has been made in the study of tumors of the thymus, although a few new subtypes have been reported. The most significant change was the subtyping by the WHO of tumors of the thymus that do not cause constitutional changes. The present Fascicle has adopted the WHO system of classification. For pathologists who are not as familiar with the WHO system, the authors extensively explain and illustrate both the morphologic and histogenetic classification systems that are its bases. Due to the changes in nomenclature, the chapter on thymic epithelial tumors has been considerably revised. The main diagnostic terms are presented along with the previous conventional morphologic and histogenetic terms, for the readers' sake. Newly recognized tumor entities, new cytologic and genetic findings, and recent references have been added. Tables have been revised to reflect new data on survival, staging, and classification. This volume will be an authoritative reference on mediastinal tumors for years to come.

Gary L. Ellis, Paul Auclair

524 pages, $165 list , ARP (2008)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

Listed under: head & neck/endocrine; Textbook chapters: Salivary glands

This volume builds upon the work of its predecessor in the third series of the Atlas of Tumor Pathology, liberally illustrating the spectrum of each tumor and disease described, while providing many new illustrations. Morphometry, flow cytometry, immunohistochemistry, gene rearrangement studies, and other molecular biologic methodologies are exciting new areas that are being developed into diagnostic procedures in the pathology laboratory. Where these methodologies are applicable to salivary gland disease, they are included. Histomorphologic evaluation, however, remains the principal and most useful method for diagnosis of salivary gland tumors and is the emphasis of this Fascicle. A differential diagnosis is included in the discussion of most tumors, and the cytopathologic features of those tumors most commonly encountered in the cytopathology laboratory are discussed.

Peter C. Burger, Bernd W. Scheithauer

596 pages, $185 list , ARP (2007)

Posted December 31, 2014

Series: AFIP Tumor 4th edition

In the decade since the publication of the Third Series Fascicle on Tumors of the Central Nervous System, many new entities have been described, prognostic significance of certain tumor subtypes established, grading systems revised, and molecular features have been correlated with tumor types and grades. Drs. Burger and Scheithauer have integrated all of these new findings, as well as classical morphological clinical and neuroradiological descriptions and illustrations, into an entirely new and completely up-to-date text/atlas that demystifies the complex subject of CNS tumors and tumor-like lesions for the general pathologists. The discussion of normal anatomy includes cytologic and radiologic correlations, as do discussions of each of the common and rare CNS lesions. Virtually all of the non-radiographic illustrations are in color, and references are current through 2006 and 2007 (the 2007 World Health Organization classification is used throughout the Fascicle). In addition to encyclopedic coverage of CNS neoplasms, approximately 15 percent of the almost 600 text pages are devoted to the numerous benign tumor-like lesions of various etiologies that may be mistaken for neoplasms. A set of fifteen Appendices is devoted to differential diagnostic algorithms which simplify the approach to a difficult specimen. The authoritative yet user-friendly approach of the authors has created a work that will be useful for many years to both pathologist and clinicians interested in tumors of the central nervous system.