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Coagulation


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Table of contents
General:books quality assurance
Physiology:antithrombin common pathway contact system extrinsic pathway fibrinolysis pathway hemostasis intrinsic pathway Protein C / Protein S anticoagulant pathway thrombomodulin
Bleeding disorders:bleeding disorders - general laboratory approach
Acquired bleeding disorders:acute phase reaction acquired dysfibrinogenemia Acquired von Willebrand disease (AVWD) amyloidosis bovine coagulation factor inhibitors disseminated intravascular coagulation (DIC) Factor V inhibitor Factor VIII inhibitor autoimmune based inhibitors in nonhemophiliac patients Factor IX inhibitor liver dysfunction lupus anticoagulant proteinuria Vitamin K deficiency / Warfarin use
Anticoagulants:danaparoid (Orgaran) heparin hirudin heparin - low molecular weight thrombolytic therapy warfarin (Coumadin)
Hereditary bleeding disorders:hereditary bleeding disorders - general algorithm for workup of hereditary bleeding disorders Factor I (fibrinogen) deficiency Factor II (prothrombin) deficiency Factor V deficiency Factor VII deficiency Factor VIII deficiency (hemophilia A) Factor IX deficiency (hemophilia B) Factor X deficiency Factor XI deficiency Factor XII deficiency Factor XIII deficiency high molecular weight kininogen deficiency / assay prekallikrein deficiency von Willebrand's disease
Acquired thrombophilia / hypercoagulopathies:acquired thrombophilia - general antiphospholipid antibodies heparin induced thrombocytopenia (HIT)
Hereditary thrombophilia / hypercoagulopathies:hereditary thrombophilia - general activated protein C resistance / Factor V Leiden antithrombin deficiency dysfibrinogenemia elevated coagulation factor levels in plasma heparin cofactor II deficiency hyperhomocysteinemia protein C deficiency protein S deficiency prothrombin gene mutation (G20210A) / hyperprothrombinemia
Coagulation laboratory tests:abnormal PT and PTT - causes activated clotting time anticardiolipin antibodies antiplasmin assay antithrombin assay bleeding time clot retraction coagulation laboratory tests - general cryoglobulin / cryofibrinogen assays D-dimer / dimerized plasmin fragment D dabigatran ecarin clotting time factor assays Factor I (fibrinogen) assay Factor V Leiden assay Factor VII assay Factor VIII assay Factor VIII inhibitor assay / Bethesda assay Factor IX assay Factor Xa assay Factor XI assay Factor XIII assay heparin induced thrombocytopenia heparinase / heparin contamination assay homocysteine assay hypercoagulation panel International normalized ratio (INR) International sensitivity index (ISI) low molecular weight heparin (LMWH) mixing studies plasminogen assay plasminogen activator antigen-1 platelet aggregation studies platelet antibodies platelet hyperaggregation studies prekallikrein assay Protein C assays Protein S assays prothrombin gene 20210A testing PT - Prothrombin time aPTT - activated partial thromboplastin time reptilase time thrombin time tPA assay von Willebrand disease testing - general von Willebrand factor antigen assay von Willebrand factor activity von Willebrand factor multimer analysis
Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:abnormal PT and PTT - causes acquired dysfibrinogenemia acquired thrombophilia - general Acquired von Willebrand disease (AVWD) activated clotting time activated protein C resistance / Factor V Leiden acute phase reaction algorithm for workup of hereditary bleeding disorders amyloidosis anticardiolipin antibodies antiphospholipid antibodies antiplasmin assay antithrombin antithrombin assay antithrombin deficiency aPTT - activated partial thromboplastin time autoimmune based inhibitors in nonhemophiliac patients bleeding disorders - general bleeding time bovine coagulation factor inhibitors clot retraction coagulation laboratory tests - general common pathway contact system cryoglobulin / cryofibrinogen assays D-dimer / dimerized plasmin fragment D dabigatran danaparoid (Orgaran) disseminated intravascular coagulation (DIC) dysfibrinogenemia ecarin clotting time elevated coagulation factor levels in plasma extrinsic pathway
F-N:factor assays Factor I (fibrinogen) assay Factor I (fibrinogen) deficiency Factor II (prothrombin) deficiency Factor IX assay Factor IX deficiency (hemophilia B) Factor IX inhibitor Factor V deficiency Factor V inhibitor Factor V Leiden assay Factor VII assay Factor VII deficiency Factor VIII assay Factor VIII deficiency (hemophilia A) Factor VIII inhibitor Factor VIII inhibitor assay / Bethesda assay Factor X deficiency Factor Xa assay Factor XI assay Factor XI deficiency Factor XII deficiency Factor XIII assay Factor XIII deficiency fibrinolysis pathway hemostasis heparin heparin - low molecular weight heparin cofactor II deficiency heparin induced thrombocytopenia heparin induced thrombocytopenia (HIT) heparinase / heparin contamination assay hereditary bleeding disorders - general hereditary thrombophilia - general high molecular weight kininogen deficiency / assay hirudin homocysteine assay hypercoagulation panel hyperhomocysteinemia International normalized ratio (INR) International sensitivity index (ISI) intrinsic pathway laboratory approach liver dysfunction low molecular weight heparin (LMWH) lupus anticoagulant mixing studies
O-Z:plasminogen activator antigen-1 plasminogen assay platelet aggregation studies platelet antibodies platelet hyperaggregation studies prekallikrein assay prekallikrein deficiency Protein C / Protein S anticoagulant pathway Protein C assays protein C deficiency Protein S assays protein S deficiency proteinuria prothrombin gene 20210A testing prothrombin gene mutation (G20210A) / hyperprothrombinemia PT - Prothrombin time quality assurance reptilase time thrombin time thrombolytic therapy thrombomodulin tPA assay Vitamin K deficiency / Warfarin use von Willebrand disease testing - general von Willebrand factor activity von Willebrand factor antigen assay von Willebrand factor multimer analysis von Willebrand's disease warfarin (Coumadin)
Coagulation books

Hoffman : 2017

Kaushansky: 2015

Key: 2017

Kottke-Marchant: 2016

McPherson: 2016



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