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Coagulation


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Editorial Board oversight: Melissa R. George, D.O. (last reviewed December 2022), Kyle Annen, D.O. (last reviewed February 2021), Patricia Tsang, M.D., M.B.A. (last reviewed September 2021)
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Table of contents
General:books physiology quality assurance
Acquired bleeding disorders:acquired dysfibrinogenemia acquired von Willebrand disease (AVWD) amyloidosis disseminated intravascular coagulation (DIC) inhibitors liver dysfunction lupus anticoagulation & antiphospholipid antibodies proteinuria Vitamin K deficiency / Warfarin use
Anticoagulants and procoagulants:4 factor PCC (pending) antiplatelet agents (pending) heparin direct oral anticoagulants (pending) heparin - low molecular weight other anticoagulants & thrombolytic therapy procoagulants (pending)
Hereditary bleeding disorders:hereditary bleeding disorders - general hereditary bleeding disorders - testing algorithm for workup of hereditary bleeding disorders Factor I (fibrinogen) deficiency Factor II (prothrombin) deficiency Factor V deficiency Factor VII deficiency Factor VIII deficiency (hemophilia A) Factor IX deficiency (hemophilia B) Factor X deficiency Factor XI deficiency Factor XII deficiency Factor XIII deficiency high molecular weight kininogen deficiency / assay prekallikrein deficiency von Willebrand disease and testing
Acquired thrombophilia / hypercoagulopathies:acquired thrombophilia - general heparin induced thrombocytopenia (HIT)
Hereditary thrombophilia / hypercoagulopathies:hereditary thrombophilia - general activated protein C resistance / Factor V Leiden antithrombin deficiency dysfibrinogenemia elevated coagulation factor levels in plasma heparin cofactor II deficiency hyperhomocysteinemia protein C deficiency protein S deficiency prothrombin gene mutation (G20210A) / hyperprothrombinemia
Coagulation laboratory tests:abnormal PT and PTT - causes activated clotting time anticardiolipin antibodies antiplasmin assay antithrombin assay bleeding time clot retraction coagulation laboratory tests - overview cryoglobulin / cryofibrinogen assays D-dimer / dimerized plasmin fragment D dabigatran ecarin clotting time factor assays Factor I (fibrinogen) assay Factor V Leiden assay Factor Xa assay heparin induced thrombocytopenia heparinase / heparin contamination assay homocysteine assay hypercoagulation panel International sensitivity index (ISI) low molecular weight heparin (LMWH) mixing studies plasminogen assay plasminogen activator antigen-1 platelet aggregation studies platelet antibodies platelet hyperaggregation studies prekallikrein assay PT - Prothrombin time PT / INR and aPTT reptilase time thrombin time tPA assay validation of assays and instruments (pending) viscoelastic hemostatic assays
Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:abnormal PT and PTT - causes acquired dysfibrinogenemia acquired thrombophilia - general acquired von Willebrand disease (AVWD) activated clotting time activated protein C resistance / Factor V Leiden algorithm for workup of hereditary bleeding disorders amyloidosis anticardiolipin antibodies antiplasmin assay antiplatelet agents (pending) antithrombin assay antithrombin deficiency bleeding time clot retraction coagulation laboratory tests - overview cryoglobulin / cryofibrinogen assays D-dimer / dimerized plasmin fragment D dabigatran direct oral anticoagulants (pending) disseminated intravascular coagulation (DIC) dysfibrinogenemia ecarin clotting time elevated coagulation factor levels in plasma
F-N:factor assays Factor I (fibrinogen) assay Factor I (fibrinogen) deficiency Factor II (prothrombin) deficiency Factor IX deficiency (hemophilia B) Factor V deficiency Factor V Leiden assay Factor VII deficiency Factor VIII deficiency (hemophilia A) Factor X deficiency Factor Xa assay Factor XI deficiency Factor XII deficiency Factor XIII deficiency heparin heparin - low molecular weight heparin cofactor II deficiency heparin induced thrombocytopenia heparin induced thrombocytopenia (HIT) heparinase / heparin contamination assay hereditary bleeding disorders - general hereditary bleeding disorders - testing hereditary thrombophilia - general high molecular weight kininogen deficiency / assay homocysteine assay hypercoagulation panel hyperhomocysteinemia inhibitors International sensitivity index (ISI) liver dysfunction low molecular weight heparin (LMWH) lupus anticoagulation & antiphospholipid antibodies mixing studies
O-Z:other anticoagulants & thrombolytic therapy physiology plasminogen activator antigen-1 plasminogen assay platelet aggregation studies platelet antibodies platelet hyperaggregation studies prekallikrein assay prekallikrein deficiency procoagulants (pending) protein C deficiency protein S deficiency proteinuria prothrombin gene mutation (G20210A) / hyperprothrombinemia PT - Prothrombin time PT / INR and aPTT quality assurance reptilase time thrombin time tPA assay validation of assays and instruments (pending) viscoelastic hemostatic assays Vitamin K deficiency / Warfarin use von Willebrand disease and testing
Other Topics:4 factor PCC (pending)
Coagulation books

Hoffman: 2022

Kaushansky: 2021

Key: 2017

Kitchens: 2018

Kottke-Marchant: 2016

McPherson: 2021

Shaz: 2018



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