DIAGNOSTIC PATHOLOGY UPDATE 2022

USCAP is a transformative leader in pathology education, creating better pathologists with updates in relevant information requisite for their performance and professional growth. The Academy is sensitive to the personal and cultural needs of practicing pathologists by providing conferences that welcome them with their families to destination venues. The 2022 Diagnostic Pathology Update course combines expert subspecialized, academic faculty, with exposure to the land of fire and ice, Iceland. From hiking on glaciers and volcanos to checking out the best that Reykjavik has to offer, DPU 2022 is the premier meeting for pathologists. Come experience all that Iceland has to offer!

Course Directors: Jason L. Hornick, MD, PhD, and Cristina Magi-Galluzzi, MD, PhD

USCAP Presents:
Modern Approaches to Classification of Hematolymphoid Neoplasms

USCAP Presents:
Dermatopathology in the Desert: Pragmatic Approach to Diagnostic Challenges

The diagnosis of neoplastic and non-neoplastic disorders represents one of the most difficult diagnostic challenges in pathology. Errors in the interpretation of skin biopsies, especially in relation to melanocytic tumors, are one of the most frequent causes for litigation in surgical pathology. There are numerous pitfalls that diagnostic pathologists need to be aware of, including lack of relevant clinical information, sampling error and the wide morphologic spectrum of both inflammatory and neoplastic disorders, often showing overlapping findings and only subtle differentiating features. Accurate diagnosis is paramount to initiate the appropriate treatment. Join expert faculty as they focus on melanocytic tumor pathology, mesenchymal tumor pathology, cutaneous lymphomas and histiocytoses and inflammatory dermatoses.

USCAP Presents:
Pearls and Palms in Surgical Pathology

Join expert pathologists as they guide you through the nomenclature, staging, and ancillary studies for your everyday surgical pathology practice. Faculty will help distinguish between what looks atypical but benign from those that look bland but are malignant. Through the case-based discussion at the Palm Springs Interactive Center, faculty will discuss histological features that are needed to make a specific diagnosis; how histology plays a role in outcomes; whether staging is important and what system to use. Topics will cover Gynecologic, Breast, Genitourinary, Gastrointestinal, Thoracic, and Head and Neck Pathology.

USCAP Presents:
Breast Pathology for All Ages: Diagnostic Pearls and Pitfalls (And How to Stay Out of Trouble)

Based on multi-institutional practices handling large volumes of breast pathology cases at established cancer centers and cumulative consultation cases, this expert faculty has identified areas that pose diagnostic and interpretative challenges in recurrent problematic areas deserving attention: intraductal epithelial proliferations and microinvasive carcinoma, lobular neoplasia including LCIS variants, papillary lesions, and benign vs malignant spindle cell lesions. The interpretation of immunohistochemical stains (IHC) with focus on predictive markers can also be challenging. This interactive microscopy course is designed to illustrate distinct challenging entities and problematic issues, with practical approaches to their resolution in real time, in the context of intimate mentoring.

USCAP Presents:
The 2022 Classification of GU Tumors: Don’t Let the New Blue Book Make You Blue

Classification, grading, staging and reporting of GU tumors have evolved significantly in recent years as molecular profiling has made a significant impact on tumor taxonomy and classification. Precision medicine and targeted therapies have emphasized the critical role of histopathological classification in prediction of prognosis and therapeutic response for cancer. These important changes are codified in the WHO Blue Book on Tumors of the Urinary System and Male Genital Organs. The 5th edition is eagerly anticipated in the spring of 2022 and is a complete revision of the 4th edition published in 2016. Expert faculty will guide attendees through the important changes and “new things” in the 5th edition WHO Blue Book in order to generate diagnoses and reports that meet the contemporary patient management needs.

USCAP Presents:
Dilemmas and Delights in Bone and Soft Tissue Pathology

Both neoplastic and non-neoplastic bone and soft tissue pathology pose significant diagnostic challenges to the practicing pathologist, due to a lack of exposure to the broad range of entities and the diverse histologic spectrum of mesenchymal pathology. As the field is ever-evolving, new entities are described, and improved diagnostic techniques are introduced. This course, presented by expert educators, aims to introduce participants to newer entities, and refamiliarize learners to old challenges in the field. Participants will learn methods for distinguishing between histologically challenging tumors of bone and soft tissue, as well as recognizing features of non-neoplastic bone pathology.

USCAP Presents:
GYNECOLOGICAL PATHOLOGY: ESSENTIAL KNOWLEDGE FOR DIAGNOSTIC PRACTICE

As a major clinical subspecialty, diagnostic gynecological pathology involves a large number of disease entities and often complex histological variants. Recent developments, particularly molecular genetic discoveries, have introduced new and reclassified entities as well as refined diagnostic criteria for many existing disease processes, calling for knowledge update for practicing pathologists. This unique four-day training course offers an engaged learning experience around a multi-headed microscope with world-class faculty delegated from the International Society of Gynecological Pathologists (ISGyP). While providing comprehensive coverage, the course emphasizes knowledge gains in morphologic recognition and using ancillary immunohistochemistry and molecular genetic studies in the most challenging areas, particularly new disease classifications/diagnostic criteria. Extensive time for one-on-one interaction with faculty constitutes the salient component of this extraordinary learning experience.

USCAP Presents:
Out with the Old and In with the New: An Updated Approach to the Cytologic Classification of Tumors

Multiple revisions and updates have recently been created for standardization of the cytologic classification of non-neoplastic and neoplastic processes in the pancreatobiliary tract, liver, thyroid, head and neck (including salivary gland), urine, kidneys, adrenal gland, lung and soft tissue. These standardized reporting schemes provide a framework for consistent categorization of cytopathology reports. They allow cytopathologists to convey clear, consistent diagnostic information, in language uniformly understood by pathologists and clinicians the world over. New developments in the diagnosis, grading and staging are not fully appreciated in the community, often leading to errors in diagnosis and impaired management. This case-based course will illustrate daily challenges, new guidelines, and practical clues to the proper handling of specimens from these sites along with accurate cytologic diagnosis of neoplasms in, and their distinction from, key cytomorphologic mimics. This will offer pathologists a unique perspective into the diagnostic morphometric signatures of key entities, which they can apply to daily practice even in the smaller hospital or private practice setting. The target audience for this course includes cytopathologists, general surgical pathologists who sign out cytopathology specimens, cytopathologists with special interest in pathology from these sites, and pathologists-in-training (residents and fellows).

USCAP Presents:
TUTORIAL IN PATHOLOGY OF THE GI TRACT, PANCREAS AND LIVER

Gastrointestinal pathology emerged as a subspecialty in the mid-to-late 1980s, coincident with utilization of endoscopy with mucosal biopsy for diagnosis and management of patients with gastrointestinal disorders. The widespread availability of endoscopy coupled with advances in tissue acquisition techniques have drastically increased the number and variety of gastrointestinal samples pathologists encounter in daily practice. As a result, pathologists are now required to provide comprehensive diagnostic information based on review of scant material. Classification of tumors is often completed based on interpretation of immunohistochemical stains coupled with molecular analyses to identify druggable targets or underlying germline conditions. Pathologists also direct the evaluation of patients with gastrointestinal complaints, particularly when patients have persistent symptoms or are immunosuppressed. Thus, they must be able to hone in on key features present in biopsy material in order to narrow the differential diagnosis and better direct patient care. This course is intended to address these needs in a succinct and pragmatic fashion.

USCAP Presents:
THORAX DECONSTRUCTED – Experts’ Guide to What Can Go Wrong Inside the Chest

Pathologists are generally unfamiliar with a variety of entities in lung, pleural, cardiac and mediastinal pathology, leading to diagnostic errors and creating practice gaps requiring attention. The panorama covered in this interactive microscopy course includes interstitial lung disease, lung infections, pulmonary vasculitis, mesothelial proliferations, mediastinal neoplasia, lung allograft rejection and mimics, heart transplant rejection and distinction from mimics, best practices for optimal triage of lung cancer samples for molecular testing, the cytology of pleural effusions, criteria for aortic vasculitis and other large vessel pathology, recognition of heart valvular pathology, criteria for diagnosis of giant cell arteritis, native heart biopsy interpretation and thoracic soft tissue neoplasms. This faculty ensemble has the professional experience to improve your practice with confidence. You will see cases that make an indelible impression. Breathe easy: this is USCAP, at the heart of education.

USCAP Presents:
BELOW THE BELT: Pitfalls and New Entities in Anorectal, Urologic and Gynecologic Surgical Pathology and Cytopathology

Pathology of the lower anogenital tract, lower urinary tract, prostate, uterus, and cervix has advanced with the identification of relevant genes, better immunohistochemical markers, and the ability to readily detect human papillomavirus (HPV) using RNA in situ hybridization. New entities have recently been recognized, refinements to existing ones are possible, and new treatment, particularly immunotherapy, are available. Expert faculty will discuss newer entities and pitfalls in these areas, while also addressing diagnostic challenges in cytology and newly adopted classification schemes.