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Openings for July 2023
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Cellular Therapy Fellowship
Opening for 2023-2024
The Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Fellowship position in the Academic Support Staff. This appointment will be for one (1) year.
This is a training position in the rapidly expanding field of cellular therapy. The candidate will work at the campuses of both the Hospital of the University of Pennsylvania (HUP) and the Children's Hospital of Philadelphia (CHOP), with three current Good Manufacturing Practice (cGMP) facilities: the Clinical Cell and Vaccine Production Facility (CVPF) at Penn, the Cell and Gene Therapy Laboratory (CGTL) and the Clinical Vector Core (CVC) both at CHOP. The cellular therapy activities at HUP and CHOP cover the entire range of standard-of-care adult and pediatric bone marrow transplant, from collection to processing to infusion. The cGMP facilities also engage in a large number clinical trials under Investigational New Drug or Device Exemptions (IND/IDEs) approved by the FDA, some of which are in collaboration with third party industrial sponsors. Examples of these IND/IDEs include the manufacturing of Chimeric Antigen Receptor T cells, virus specific cytotoxic T lymphocytes, and selective T/B cell depleted transplant grafts. The candidate will have a wide exposure of different cGMP labs within walking distance, learn the set up and operation of cGMP facilities, in addition to the actual manufacturing processes.
Cellular therapy is a highly regulated field. The candidate will also engage in managing different quality aspects of cell manufacturing, participate in drafting IND/IDE Chemistry, Manufacturing and Controls (CMC) sections, including response to FDA inquiries. There are numerous opportunities for quality improvement projects. Didactic training, either one-on-one with a faculty or part of more formal course, is also available. The candidate is encouraged to tailor the one-year program to suit individual background and needs, while still gaining enough exposure to become proficient in all areas. Ideally, a successful candidate would leave the program feeling confident to direct a cell therapy facility.
Applicants must have an M.D. or Ph.D. or equivalent degree and have demonstrated excellent qualifications in education, research, and clinical care. Documents needed: Curriculum Vitae; Personal Statement; three potential references.
Applications and Inquiries to:
Yongping Wang, MD, PhD
Director, Cell and Gene Therapy Lab
Children's Hospital of Philadelphia
Email: wangy2@chop.edu
[#12349, exp. 6 August 2023]
