2 Staff Pathologist Positions

TUCSON, ARIZONA (USA). You will provide pathology support to internal groups, business units and functional areas. Makes medical/pathology related decisions and recommendations at the technical and tactical level in support of the related business unit objectives. Applies pathology concepts that contribute to development of company concepts and principles to achieve objectives in creative and effective ways on both new and existing products. Supports various ongoing assay and automated platform development projects across the company involving technologies such as immunohistochemistry (IHC) and in situ hybridization (ISH). May serve as the medical representative on project core teams and contribute to pathology related aspects of specific development projects. Monitors work to ensure quality, and continuously promote quality first time.

Responsibilities:
  •   Provides pathology and slide reading support to R&D Life Sciences, Tissue Bank, Manufacturing, Customer Support, Safety Board Meetings, and MI as
    directed.
  •   Provides pathology and slide reading support for FDA submissions, clinical trials, and Pharma clients.
  •   Supports research and development activities for primary antibodies, detection systems, probes and special stains.
  •   Makes suggestions to improve work processes. Gives advice on future pathology and medical needs.
  •   May serve as the medical representative on project core teams and contribute to pathology related aspects of specific development projects.
  •   May read clinical trial live patient slide samples for CAP/CLIA lab.
  •   Miscellaneous duties as assigned.

Formal Training/Education:
  •   M.D. - US M.D. Pathologist with Board Certification in Anatomic Pathology required
  •   Active State License required

Experience:
  •   Residency trained (Fellowship trained preferred), with 1 year of experience in clinical practice or industry.
  •   Experience in immunohistochemistry, cytology, molecular and genetics

Knowledge, Skill, or Ability:
  •   Knowledge of basic Anatomic Pathology.
  •   Demonstrated record of accomplishments, e.g., pathology related posters, abstracts, publications, concentrated area of interest/medical directorship.
  •   Skill in utilizing customary computer programs (word processing, spreadsheet, email, etc.).
  •   Skill and ability in communicating

Apply Here:
  •   https://roche.wd3.myworkdayjobs.com/roche-ext/job/Tucson/Staff-Pathologist-I_202108-123310
  •   https://roche.wd3.myworkdayjobs.com/roche-ext/job/Tucson/Staff-Pathologist-I_202108-123446

[26 August 2021, #11296]

GSK - Oncology R & D
Translational and Computational Pathologist
Philadelphia or Waltham, MA

PHILADELPHIA, PENNSYLVANIA / WALTHAM, MASSACHUSETTS (USA). GSK seeks a Translational and Computational Pathologist to integrate knowledge of disease mechanisms with drug mechanism of action to inform drug development. The successful candidate will 1) work closely with R & D scientists who discover/develop drugs for the treatment of cancer and discover and develop biomarkers for pharmacodynamic assessment and patient selection for clinical trials; and, 2) work with the Artificial Intelligence/Machine Learning (AI/ML) team to develop computational pathology capabilities and applications in design, validation and construction of novel predictive algorithms based upon anatomic pathology images. The role works across R&D to ensure that strategies for the treatment/cure of disease are based on accurate analysis of pathogenetic mechanisms.

Key Responsibilities:

• Provides expertise in the molecular, cellular, systems biology, and pathogenic mechanisms of disease
• Provides pathology expertise and support for drug, biomarker and diagnostic programs in oncology
• Applies a broad range of diagnostic modalities and translational pathology tools and technology, including assay or digital pathology image analysis algorithm development
• In partnership with the Biomarker Leads within the EMU will evaluate/implement novel tissue-based assays and/or analytical techniques
• Aid in integrating data across different diagnostic platforms in partnership with the Precision Medicine & Companion Diagnostics team
• Applies special skills in anatomic/computational pathology including immunohistochemistry, multiplexed immunofluorescence; ii) Spatial or single-cell transcriptomics iii) Quantitative image analysis including artificial intelligence or machine learning, or iv) Advanced microscopy applications
• Works with the EMU and AI/ML organization on the development of computational pathology capabilities and applications, involved in the design, validation and construction of training and validation data

• MD with Board Certification in Anatomic Pathology with subspecialty fellowship training or two + years of postdoctoral research experience in oncology
• Excellent traditional diagnostic pathology skills with a strong ability to interpret pathology data in the context of a deep understanding of molecular and cellular biology

• MD/PhD
• Board Certification in Hematopathology or Molecular Genetic Pathology

• Please apply at: https://gsk.wd5.myworkdayjobs.com/GSKCareers/job/USA---Pennsylvania---Upper-Providence/Translational-Pathologist_295573-1
• For additional information, submit your CV to Giorgia at: giorgia.2.signoretto@gsk.com

Genitourinary Pathologist

SPRING HOUSE, PENNSYLVANIA (USA).

Job Description:
Janssen Research & Development, LLC, a member of the Johnson & Johnson Family of Companies, is recruiting for a Genitourinary Pathologist, in the Oncology Therapeutic Area located in Spring House, PA.

As an Associate Scientific Director (Genitourinary Pathologist), you will act as the pathology subject matter expert in Oncology Translational Research responsible for analytical validation of immunohistochemistry assays developed by the Molecular Pathology Laboratory and provide pathology-related consultation services across the Janssen Oncology portfolio.

Responsibilities Include:
  •   Scientific management of the design, execution and analytical validation plan of immunohistochemistry assays for the evaluation of predictive and
    pharmacodynamic biomarkers in human tissues.
  •   Approve validation reports and technical reports for molecular pathology assays. Contribute to relevant regulatory documents when required.
  •   Approve assay transfer quality for assays transferred to external contract research laboratories and companion diagnostic partners in support of clinical
    development and companion diagnostic development.
  •   Perform technical audits of contract laboratories, including companion diagnostic site laboratories, and report findings in the form of written reports.
  •   Provide scientific direction and expertise in the area of pathology for both non-clinical and clinical study experiments, including writing relevant sections of
    clinical trial protocols.
  •   Communicate pathology results in the form of written and oral reports and disseminate regular written project updates to line management and relevant
    compound development team members.
  •   Evaluate, interpret and report pathology based clinical study conclusions to Translational Research representatives, to clinical development teams and to
    physicians participating in clinical trials as appropriate.
  •   Maintain familiarity with CAP and CLIA regulations
  •   Maintain familiarity with relevant regulatory requirements surrounding companion diagnostic development.

Qualifications:
  •   M.D. or D.O. degree with board certification in Anatomic Pathology is required.
  •   Extensive experience and/or subspecialty training in Genitourinary pathology is preferred.
  •   Oncology and immunohistochemistry assay validation experience is preferred.
  •   Experience in digital image analysis is desired.

Apply here: https://jobs.jnj.com/jobs/2105948348W?lang=en-us&previousLocale=en-US

[23 August 2021, #11272]