By Subspecialty

Bone, joints & soft tissue
Bone & joints: AE1 / AE3 BCOR brachyury CD1a CD68 CD99 CD138 CIC-DUX4 ERG FLI1 GRM1 (pending) H3K36M (pending) H3G34W (pending) MDM2 MUM1 NKX2.2 (pending) S100 SATB2 SOX9
Soft tissue: AE1 / AE3 ALK1 caldesmon CAMTA1 CD31 CD34 CD99 CDK4 D2-40 DDIT3 (pending) desmin DOG1 EBER EMA ERG factor XIIIa FLI1 FOSB (pending) GLUT1 H3K27me3 HHV8 / LANA1 HMB45 c-kit / CD117 MDM2 MelanA MUC4 MYOD1 myogenin NKX2.2 (pending) NR4A3 (pending) pan-TRK PROX1 (pending) RB1 S100 SDHB SMARCA4 / BRG1 SMARCB1 / IN1 SMA SOX10 STAT6 SYT / SSX (pending) TFE3 TLE1 WT1

Breast
androgen receptor calponin CK5/6 and CK5 CK7 E-cadherin ER GATA3 GCDFP-15 HER2 breast mammaglobin p40 p63 p120 catenin PDL1 22C3 PDL1 SP142 PR SMMHC / smooth muscle myosin heavy chain SOX10 TRPS1

Derm
Keratinocytic and adnexal neoplasms: adipophilin (sebaceous neoplasms) (pending) AE1 / AE3 BerEP4 (BCC) CD10 (trichoepithelioma versus BCC) CD34 (trichoepithelioma versus BCC) CEA CK5/6 CK7 CK20 EMA PHLDA1 (trichoepithelioma versus BCC) (pending) p40 p63
Spindle cell neoplasms: AE1 / AE3 ALK CD10 CD31 CD34 CD99 desmin ERG Factor XIIIa SMA vimentin
Specialized markers: BAP1 BRAF MLH1 MLH3 (pending) MSH2 MSH6 PMS2 p16

GI
Anus: HPV p16 p53 treponema IHC Warthin-Starry
Colon / appendix: CDX2 CK20 CMV chromogranin colon cancer biomarker testing (including MSI / Lynch) HER2 colon Ki67 MLH1 MSH1 MSH2 MSH6 PMS2 SATB2 synaptophysin
Esophagus: CMV GMS HER2 stomach GEJ p63
Gallbladder: CK7 CK19 CK20 DPC4 / SMAD4
Liver: arginase1 BSEP (pending) CMV HepPar1 iron MDR3 (pending) PAS reticulin serum amyloid A / SAA trichrome
Pancreas: IgG4 inhibin Ki67 SMAD4 / DPC4 SOX11 trypsin (pending)
Small intestine: chromogranin c-kit / CD117 DOG1 Ki67 synaptophysin
Stomach: chromogranin c-kit / CD117 DOG1 desmin EBER1 / 2 / LMP gastrin (pending) Helicobacter pylori HER2 stomach GEJ INSM1 Ki67 S100 SMA synaptophysin Warthin-Starry

GU / adrenal
Adrenal: calretinin chromogranin CK7 GATA3 GD2 (pending) inhibin MelanA S100 synaptophysin TTF1
Bladder: CK7 CK20 GATA3 p40 p63 PDL1 22C3 uroplakin II
Kidney: AMACR CAIX CD10 CK7 c-kit / CD117 fumarate hydratase INI1 / SMARCB1 MelanA PAX8 RCC SDHB SMA TFE3 vimentin WT1
Penis: CK5/6 and CK5 HPV p40 p63
Prostate: androgen receptor AMACR CK5/6 and CK5 ERG NKX3.1 p63 prostein (P501S) PSA PSAP PSMA
Testis: AFP CD30 CK7 c-kit / CD117 D2-40 glypican 3 hCG inhibin OCT3/4 PLAP SALL4

Gyn
Cervix: CEA CK7 ER GATA3 HIK1086 HPV Ki67 MUC6 p16 p40 p53 p63 PAX8 PR vimentin
Ovary: AE1/AE3 AFP ARID1A calretinin CK7 CD30 EMA ER FOXL2 Glypican 3 hCG HNF-1B (pending) inhibin Napsin A OCT 3/4 p16 p53 PAX8 PR PTEN reticulin SALL4 SF1 WT1
Placenta: p57
Uterus-endometrium: ARID1A EMA ER GATA3 hCG HNF-1B (pending) HPL inhibin Napsin A p16 p53 p57 PAX8 PR PTEN
Uterus-mesenchymal: ALK BCOR caldesmon CD10 Cyclin D1 desmin ER HMB45 IFITM1 MelanA myogenin / myoglobin p16 p53 PR smooth muscle actin
Vulva & vagina: desmin HMGA2 (pending) HPV Ki67 p16 p53

Head & neck
Mandible & maxilla: AE1 / AE3 ALK beta catenin BRAF (IHC) calretinin CD56 CK19 FOSB (pending) S100 SATB2
Nasal, sinonasal & nasopharynx: AE1/AE3 beta catenin CD45 CD99 CDX2 chromogranin CK5/6 CK7 CK20 EBER1 EMA/MUC1 HPV INI1 myogenin NUT p16 p40 S100 SMA SOX10 synaptophysin
Oral cavity & oropharynx stains: acid fast calponin CD34 CK5/6 CK7 CK20 desmin EBER1 GATA3 GMS HSV (pending) mucicarmine p16 p40 p63 PAS S100 SMA SOX10 treponema IHC
Salivary: androgen receptor beta catenin calponin CK5/6 and CK5 CK7 c-kit / CD117 DOG1 GATA3 IgG (pending) IgG4 LEF1 mammaglobin mucicarmine MYB NR4A3 (pending) p40 p63 PLAG1 S100 SMA SOX10
Thyroid: beta catenin calcitonin CEA chromogranin CK19 c-kit / CD117 Congo red galectin3 HBME PAX8 PTEN thyroglobulin TTF1

Hemepath

Hodgkin lymphoma: ALK1 CD3 CD15 CD20 CD30 CD45 (LCA) EBER1 / 2 / LMP PAX5
Leukemia: CD3 CD34 CD68 c-kit / CD117 E-cadherin MPO NPM1 (pending) PAX5 TdT
Non-Hodgkin lymphoma & myeloma: BCL6 CD3 CD5 CD10 CD15 CD20 CD23 CD30 CXCR3 kappa & lambda light chains Ki67
Nonneoplastic lymph node & bone marrow: AFB CD1a CD34 CD41 CD45 (LCA) CD61 CD68 c-kit / CD117 CMV E-cadherin EBER1 / 2 / LMP EMA Factor VIII GMS hemoglobin A   HHV8 IgG4 iron myeloperoxidase parvovirus B19   PAS reticulin S100 trichrome Warthin-Starry

Lung & pleura
ALK calretinin chromogranin CK5/6 and CK5 CK7 D2-40 EGFR Napsin A PDL1 22C3 synaptophysin TTF1 WT1

Medical renal
adenovirus C4d (pending) calcium / von Kossa CD68 CMV collagen / type IV Congo red COX2 DNAJB9 (pending) EBER1 / 2 / LMP FN1 (pending) HSV (pending) Jones silver Masson trichrome myogenin / myoglobin NCCT (pending) PAX2 Periodic acid Schiff (PAS) prealbumin (pending) SV40 (pending)

Neuropath
CNS nontumor: alpha-synuclein AT8 (pending) beta amyloid Luxol fast blue p62 (pending) TDP-43 (pending)
CNS tumor: ACTH (pending) ATRX BRAF V600E H3K27M (pending) H3K36M (pending) GFAP IDH1 (R132H) NeuN NFP / neurofilament Olig2 Pit1 SSTR2A synaptophysin Tpit
Muscle nontumor: acid phosphatase alkaline phosphatase ATPases (pending) COX Gomori trichrome (pending) myophosphorylase (pending) NADH nonspecific esterase Oil Red O PAS phosphofructokinase (pending) SDH (pending)

Companion diagnostic tests
c-kit / CD117 EGFR ER HER2 breast HER2 colon HER2 stomach GEJ PDL1 22C3 PDL1 SP142 PDL1 SP263 (pending) PR TROP2 (pending)


Alphabetical listing

General: books IHC procedure common panels / unknown primary enzyme cytochemistry troubleshooting (pending)

2-succino-cysteine ABCC2 acid fast acid phosphatase ACTH (pending) actin-general / cardiac actin-alpha smooth muscle actin-muscle specific adenovirus adipophilin (pending) AE1/AE3 (cytokeratin) albumin Alcian blue ALK alkaline phosphatase alpha-1-antichymotrypsin alpha-1 antitrypsin alpha-fetoprotein (AFP) alpha-synuclein AMACR amyloid beta / APP androgen receptor arginase1 ARID1A AT8 (pending) ATDX (ATRX) ATM auramine-rhodamine

B72.3 BAP1 BCL1 BCL10 (pending) BCL2 BCL6 BCOR BerEP4 beta catenin BOB1 brachyury BRAF BRAF-melanoma BSEP (pending)

C4d (pending) CA 19-9 CA125 calcitonin calcium caldesmon calponin calretinin CAMTA1 carbonic anhydrase IX / CAIX cathepsin K

CD markers: CD markers-general 1-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80-89 90-99 100-109 110-119 120-129 130-139 140-149 150-159 160-169 170-199 200-209 210-229 230-239 240-269 270-279 280+

CDK4 CDX2 CEA chloroacetate esterase chromogranin c-kit / CD117 claudins CMV collagen / type IV Congo red copper / rhodamine COX COX2 C reactive protein (pending) Crystal Violet (pending) CXCL13 (pending) CXCR3 Cyclin D1

Cytokeratins: general uncommon CK5/6 and CK5 CK7 CK8 CK8/18 (pending) CK10 CK14 CK17 CK18 CK19 CK20 34betaE12 / HMWCK / high molecular weight 35betaH11 AE1/AE3 CAM5.2 MNF116 OSCAR

D2-40 DBA-44 DDIT3 (pending) deltaNp63 desmin dicer Diff-Quik (pending) DOG1 DPC4 / SMAD4 DUX4

E-cadherin EBER1 / 2 / LMP EBNA2 (pending) EGFR elastic fibers EMA EpCAM ERG estrogen receptor/ER ETV6-NTRK3 EWSR1 EZH2

Factor VIII Factor XIIIa Fas/CD95 Fas ligand/CD178 fascin filaggrin FLI1 FMC7 FN1 (pending) Fontana-Masson FOS (pending) FOSB (pending) FOXL2 FOXP3 fumarate hydratase

Galectin3 gastrin (pending) GATA3 GCDFP-15 GCET (pending) GD2 (pending) GFAP Giemsa / Helicobacter pylori glucagon (pending) GLUT1 glutamine synthetase (pending) glycophorin A glypican 3 GMS gram stain granzyme B, M

H3K27M (pending) H3K27me3 H3K36M (pending) Hansel HBME hCG HepPar1 HER2 breast HER2 colon HER2 stomach GEJ HGAL HHF35 HHV8 HIK1083 HLA-DR HMB45 HNF1β (pending) HMGA2 (pending) HPL HPV hSNF5 HSP70 (pending) HSV (pending) HTLV1 (pending)

IDH1 (R132H) IFITM1 IgA IgD IgG IgM (pending) IgG4 IMP3 inhibin INI1 INSM1 insulin (pending) IRF4 iron islet 1 (Isl1) (pending)

Jones methenamine silver (JMS) kappa & lambda light chains Ki67 KSHV

L1-CAM (pending) LANA Leder LEF1 Leu7 LFABP (pending) lipid lipochrome LMO2 Luxol fast blue lysozyme

mammaglobin mast cell tryptase (MCT) (pending) MART1 MCPyV MDM2 MDR MDR3 (pending) MEF2B (pending) MelanA MIB1 mic2 microphthalmia transcription factor (MITF) MLH1 MLH3 (pending) MOC31 Movat pentachrome (pending) MSA MSH1 MSH2 MSH6 MSI-Lynch syndrome MTAP (pending) mucins MUC1 MUC2-6 MUM1 MYB MYC myeloperoxidase MyoD1 myogenin / myoglobin

NB84 (pending) NADH N-CAM NCCT (pending) Napsin A NeuN neuron specific enolase NF1 / NF2 NFP / neurofilament NGFR / p75 (pending) NKI-C3 NKX2 (pending) NKX3.1 nonspecific esterase NPM1 (pending) NTRK NUTM1

OCT2 OCT3/4 Oil Red O Olig2 orcein (pending)

P glycoprotein p16 p21 p40 p53 p57 p62 (pending) p63 p120 catenin P504S Pan-TRK PAP Parvalbumin (pending) PAS PAX2 PAX5 PAX8 PCNA PD-1 PDL1 22C3 PDL1 SP142 PDL1 SP263 (pending) PECAM1 perforin (pending) PGP9.5 (pending) PHLDA1 (pending) phosphohistone H3 Phospho-Smad2 (pending) Pit1 PLAG1 PLAP PMS2 podoplanin PRAME PRDM1 (BLIMP1) (pending) prealbumin (pending) progesterone receptor/PR prostein PROX1 (pending) PSA PSAP PSMA PTEN PTH (pending) PU.1

RB1 RCC reticulin ROS1

S100 S100A1 (pending) S100P SALL4 SATB2 SDH (pending) SDHB serum amyloid A/SAA SF1 Sirius red SMAD4 / DPC4 SMARCA4 SMMHC / smooth muscle myosin heavy chain smoothelin somatostatin (pending) SOX2 SOX9 SOX10 SOX11 SSTR2A STAT6 Sudan Black B SV40 (pending) synaptophysin SYT / SSX (pending)

TCL1 TCF4 (pending) TCR (pending) TDP-43 (pending) TdT TERT TFE3 thrombomodulin thyroglobulin TLE1 TLE3 (pending) Toluidine blue (pending) toxoplasma (pending) Tpit TRAP treponema IHC trichrome TROP2 (pending) trypsin (pending) TSC1/2 TTF1 TSH (pending) tyrosinase

Unknown primary uric acid uroplakin II uroplakin III

VHL villin vimentin VIP (pending) vWF VZV (Varicella-zoster virus) (pending)

Warthin-Starry Wright-Giemsa WT1 YAP1 ZAP70 (pending) Ziehl-Neelsen

Superpages: entire chapter images virtual slides