General: anatomy / histology atrophy biopsy embryology

Development: adrenal cortical rests androgen insensitivity congenital adrenal hyperplasia cryptorchidism cystic dysplasia de la Chapelle dysgenetic male pseudohermaphroditism excurrent duct obstruction germ cell aplasia gonadal dysgenesis-mixed gonadal dysgenesis-pure gonadotropin deficiency hypospermatogenesis infertility Klinefelter syndrome macroorchidism male pseudohermaphroditism maturation arrest persistent Müllerian duct polyorchism rete testis dysgenesis Sertoli-infantile testis splenogonadal fusion testicular regression syndrome / anorchia testotoxicosis true hermaphroditism tubular sclerosis

Nonneoplastic lesions: chemotherapy chylocele cysts endometriosis-like lesion epididymitis fibrous pseudotumor granulomatous orchitis hematocele hernia sac with mesothelial entrapment hydrocele infectious orchitis malakoplakia meconium periorchitis paratesticular fibrous pseudotumor proliferative funiculitis radiation effects Sertoli hyperplasia silicon implants sinus histiocytosis with massive lymphadenopathy smooth muscle hyperplasia spermatocele testicular adrenal rest tumor / tumor of adrenogenital syndrome torsion tunica albuginea cysts varicocele vasculitis vasitis nodosa

Testicular tumors: general classification

Germ cell tumors: general angiosarcoma carcinoid / well differentiated neuroendocrine tumor chondrosarcoma choriocarcinoma cystic trophoblastic tumor dermoid cyst diffuse embryoma embryonal carcinoma epidermoid cyst epithelial trophoblastic tumor germ cell neoplasia in situ (GCNIS) NSGCT-general osteosarcoma placental site trophoblastic tumor PNET polyembryoma post-chemotherapy regressed germ cell tumor seminoma spermatocytic tumor teratoma teratoma with somatic type malignancy yolk sac tumor

Sex cord-stromal tumors: general adult granulosa cell fibroma-thecoma gonadoblastoma intratubular large cell hyalinizing Sertoli cell neoplasia juvenile granulosa cell large cell calcifying Sertoli cell Leydig cell mixed / unclassified sex cord - stromal mixed-other Sertoli cell NOS Sertoli cell sclerosing

Other testicular tumors: anaplastic large cell lymphoma granulocytic / myeloid sarcoma hemangioma interdigitating dendritic cell tumor juvenile xanthogranuloma lymphoma metastases plasmacytoma

Testis stains: AFP CD30 CD117/KIT D2-40 Glypican 3 HCG inhibin OCT3/4 PLAP SALL4

Miscellaneous: staging features to report grossing

Paratesticular tumors: adenomatoid Brenner tumor desmoplastic small round cell lymphoma male adnexal tumor of probable Wolffian origin melanotic neuroectodermal mesothelioma mucinous adenocarcinoma mucinous borderline ovarian epithelial type serous borderline tumor serous carcinoma well differentiated papillary mesothelioma

Epididymal tumors: adenocarcinoma cribriform hyperplasia papillary cystadenoma

Rete testis: adenocarcinoma adenomatous hyperplasia cystic dilation (transformation) cystic dysplasia sertoliform cystadenoma

Spermatic cord tumors: general aggressive angiomyxoma angiomyofibroblastoma embryonal rhabdomyosarcoma fibromatosis hemangioma leiomyoma (pending) leiomyosarcoma lipoma liposarcoma paraganglioma pleomorphic sarcoma rhabdomyoma rhabdomyosarcoma rhabdomyosarcoma-spindle cell vascular myxolipoma

Superpages: entire chapter images virtual slides


Index (Alphabetical table of contents)
A-E: adenocarcinoma (epididymis) adenocarcinoma (rete testis) adenomatoid tumor adenomatous hyperplasia (rete testis) adrenal cortical rests adrenogenital syndrome adult granulosa cell aggressive angiomyxoma anaplastic large cell lymphoma anatomy / histology androgen insensitivity angiomyofibroblastoma angiosarcoma atrophy biopsy Brenner tumor carcinoid / well differentiated neuroendocrine tumor chemotherapy related lesions chondrosarcoma choriocarcinoma chylocele classification-neoplasms (testis) congenital adrenal hyperplasia cribriform hyperplasia cryptorchidism cystic dilation (transformation) cystic dysplasia (rete testis) cystic dysplasia (testis) cystic trophoblastic tumor cysts-general de la Chapelle dermoid cyst desmoplastic small round cell diffuse embryoma dysgenetic male pseudohermaphroditism embryology embryonal carcinoma embryonal rhabdomyosarcoma endometriosis-like lesion epidermoid cyst epididymitis epithelial trophoblastic tumor excurrent duct obstruction

F-N: features to report-testicular tumors fibroma-thecoma fibromatosis fibrous pseudotumor germ cell aplasia germ cell neoplasia in situ (GCNIS) germ cell tumors-general gonadal dysgenesis-mixed gonadal dysgenesis-pure gonadoblastoma gonadotropin deficiency granulocytic sarcoma / myeloid sarcoma granulomatous orchitis grossing-testicular tumors hemangioma (spermatic cord) hemangioma (testis) hematocele hernia sac with mesothelial entrapment hydrocele hypospermatogenesis infectious orchitis infertility interdigitating dendritic cell tumor intratubular large cell hyalinizing Sertoli cell neoplasia juvenile granulosa cell juvenile xanthogranuloma Klinefelter syndrome large cell calcifying Sertoli cell leiomyosarcoma Leydig cell lipoma (spermatic cord) liposarcoma lymphoma (paratesticular) lymphoma (testicular) macroorchidism malakoplakia male adnexal tumor of probable Wolffian origin male pseudohermaphroditism maturation arrest meconium periorchitis melanotic neuroectodermal tumor mesothelioma metastases to testis mixed-other mixed / unclassified sex cord - stromal mucinous borderline mucinous adenocarcinoma neoplasms (testis)-general NSGCT-general

O-Z: osteosarcoma ovarian epithelial type papillary cystadenoma paraganglioma paratesticular fibrous pseudotumor persistent Müllerian duct placental site trophoblastic tumor plasmacytoma pleomorphic sarcoma PNET polyembryoma polyorchism post-chemotherapy germ cell tumors proliferative funiculitis radiation effects regressed germ cell tumor rete testis dysgenesis rhabdomyoma rhabdomyosarcoma rhabdomyosarcoma-spindle cell seminoma serous borderline tumor serous carcinoma Sertoli cell NOS Sertoli cell sclerosing Sertoli cell tumor-infantile testis Sertoli hyperplasia sertoliform cystadenoma (rete testis) sex cord stromal tumors-general silicon implants sinus histiocytosis with massive lymphadenopathy smooth muscle hyperplasia spermatic cord tumors-general spermatocele spermatocytic tumor splenogonadal fusion staging-testicular tumors teratoma teratoma with somatic type malignancy testicular regression syndrome / anorchia testotoxicosis torsion true hermaphroditism tubular sclerosis tunica albuginea cysts varicocele vascular myxolipoma vasculitis vasitis nodosa well differentiated papillary mesothelioma yolk sac tumor