Appendix
General
Features to report & grossing


Topic Completed: 1 August 2012

Minor changes: 29 July 2020

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Table of Contents
Features to report | Grossing
Cite this page: Mansouri J. Features to report & grossing. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/appendixfeatures.html. Accessed August 12th, 2020.
Features to report
  • Tumor size
  • Histologic type
  • Histologic grade
  • Depth of invasion
  • Angiolymphatic invasion
  • Perineural invasion
  • Margin involvement (surgical, radial, mesenteric)
  • Peritumoral satellite nodules (for appendiceal carcinomas)
  • Lymph node involvement (total involved, total examined)
  • Mitotic rate and Ki-67 labeling index (for appendiceal carcinoids)
  • Additional findings such as diverticula

Notes:
  • As of June 2012, there are updated College of American Pathologists (CAP) protocols for both appendiceal adenocarcinomas and well-differentiated neuroendocrine tumors (NET) of the appendix: visit CAP.org and search for "Cancer Protocols and Checklists"
  • Staging for NETS does not include poorly differentiated (high-grade, G3) neuroendocrine carcinomas, small cell carcinomas, and goblet cell carcinoids (use CAP protocol for appendiceal carcinomas)

Grossing
  • Describe length and greatest diameter, external surface (fibrinous exudate, perforation), luminal patency, mucosa, details of any unusual lesions
  • Submit longitudinal or cross section of distal tip (common site of carcinoid tumors), cross sections from middle and margin of resection
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