Other nonneoplastic

Lymphoid hyperplasia

Last author update: 1 August 2012
Last staff update: 12 February 2024 (update in progress)

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PubMed Search: Lymphoid hyperplasia appendix

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Cite this page: Mansouri J. Lymphoid hyperplasia. website. Accessed February 22nd, 2024.
Definition / general
  • Normal appendix is rich in lymphoid tissue
  • Hyperplasia may be associated with acute appendicitis (uncertain if cause or effect)
Gross description
  • May be present at entrance to cecum
Microscopic (histologic) description
  • Marked swelling and thickening of mucosa and submucosa, with virtual luminal obliteration
  • Older patients also have plasma cells and eosinophils
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