Other nonneoplastic

Lymphoid hyperplasia

Topic Completed: 1 August 2012

Minor changes: 20 August 2019

Copyright: (c) 2003-2019,, Inc.

PubMed Search: Lymphoid hyperplasia appendix

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Cite this page: Mansouri J. Lymphoid hyperplasia. website. Accessed October 18th, 2021.
Definition / general
  • Normal appendix is rich in lymphoid tissue
  • Hyperplasia may be associated with acute appendicitis (uncertain if cause or effect)
Gross description
  • May be present at entrance to cecum
Microscopic (histologic) description
  • Marked swelling and thickening of mucosa and submucosa, with virtual luminal obliteration
  • Older patients also have plasma cells and eosinophils
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