Bladder, ureter & renal pelvis
Other nonneoplastic
Endosalpingiosis
Author: Alcides Chaux, M.D.
Topic Completed: 1 July 2011
Minor changes: 29 October 2021
Copyright: 2003-2021, PathologyOutlines.com, Inc.
PubMed Search: Endosalpingiosis
Table of Contents
Definition / general | Terminology | Epidemiology | Sites | Etiology | Clinical features | Case reports | Treatment | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Chaux A. Endosalpingiosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/bladderendosalpingiosis.html. Accessed November 27th, 2021.
Definition / general
- Involvement of lamina propria and muscularis propria by tubules and cysts with tubal type epithelium (ciliated cells, intercalated cells, peg cells)
Terminology
- Called Müllerianosis if 2 of 3 related entities (endocervicosis, endometriosis or endosalpingiosis) are present (Mod Pathol 1996;9:731)
Epidemiology
- Very uncommon
- Usually seen in women of childbearing age
Sites
- Posterior wall or posterior dome
Etiology
- Metaplastic (Müllerian metaplasia) or implantative (similar to endometriosis)
Clinical features
- Suprapubic pain, urinary frequency, dysuria
- May occur after surgery in some cases
Case reports
- 54 year old woman with pure endosalpingiosis, possibly implanted after surgery (Int J Surg Pathol 2010;18:381)
Treatment
- Excision; may recur (Urology 2004;64:1031)
Gross description
- May form mass on posterior wall of bladder
Microscopic (histologic) description
- Involvement of lamina propria and muscularis propria by tubules and cysts of Müllerian type epithelium
- May replace urothelium and form polypoid projections into bladder lumen
- Tubules and cysts are round / oval, may have prominent branching
- Glands are lined by tubal type epithelium (ciliated cells, intercalated cells, peg cells)
- No atypia, no mitotic figures, no necrosis
Microscopic (histologic) images
AFIP images
Ovary: glands lined by ciliated epithelium lie in fibrous stroma
Ovary: ciliated,
secretory and
intercalated cells
line the cystic space
Differential diagnosis
- Adenocarcinoma:
- Marked atypia, invasive borders, usually not ciliated and lacks 3 types of tubal cells
