Bladder, ureter & renal pelvis

Squamous cell neoplasms

Verrucous carcinoma

Topic Completed: 1 August 2019

Minor changes: 19 November 2021

Copyright: 2003-2021,, Inc.

PubMed Search: Verrucous squamous cell carcinoma[title]

Related topics: Squamous cell carcinoma

Monika Roychowdhury, M.D.
Page views in 2020: 336
Page views in 2021 to date: 420
Cite this page: Roychowdhury, M. Verrucous carcinoma. website. Accessed December 6th, 2021.
Definition / general
  • Almost all cases are associated with Schistosoma hematobium infection
  • Indolent growth, spreads by direct extension
  • Does not metastasize, although may develop foci of invasive squamous cell carcinoma
Gross description
  • Exophytic, papillary tumor which projects into bladder lumen
Microscopic (histologic) description
  • Bulbous fronds of well differentiated, acanthotic epithelium with pushing margin, minimal atypia
  • No/rare mitotic figures
  • May resemble condyloma focally
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